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Unlabelled: ICANS is a common form of neurological immunotoxicity from CAR T-cell therapy (CAR-T). While high tumor burden, product type and cell dose are established risk factors, there are many unknowns. Our objective was to characterize novel neurological and non-neurological risk factors for the development of ICANS in subjects who received CAR-T.
View Article and Find Full Text PDFNutr Health
January 2025
Department of Human Nutrition, Faculty of Human Nutrition, Tokyo Kasei-Gakuin University, Chiyoda-ku, Tokyo, Japan.
Background: Maternal time constraints lead to a lack of vegetable provision to children. Mothers use homemade meal strategies under time constraints; however, these strategies have not been well investigated.
Aim: This study aimed to classify the homemade meal strategies used by mothers under time constraints and to examine their association with the provision of vegetable dishes.
Ann Transl Med
December 2024
Division of Cardiothoracic Surgery, Department of Surgery, The Chinese University of Hong Kong, Hong Kong, China.
Background And Objective: Patients with thoracic aortic aneurysm and dissection (TAAD) are often asymptomatic but present acutely with life threatening complications that necessitate emergency intervention. Aortic diameter measurement using computed tomography (CT) is considered the gold standard for diagnosis, surgical planning, and monitoring. However, manual measurement can create challenges in clinical workflows due to its time-consuming, labour-intensive nature and susceptibility to human error.
View Article and Find Full Text PDFJ R Soc Interface
January 2025
Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY, USA.
Influenza forecasts could aid public health response as shown for temperate regions, but such efforts are more challenging in the tropics and subtropics due to more irregular influenza activities. Here, we built six forecast approaches for influenza in the (sub)tropics, with six model forms designed to model seasonal infection risk (i.e.
View Article and Find Full Text PDFJ Nucl Med
January 2025
Department of Nuclear Medicine, University Hospital Würzburg, Würzburg, Germany
Dosimetry is integral to informed implementation of radiopharmaceutical therapies, enabling personalized treatment planning and ensuring patient safety by calculating absorbed doses to organs and tumors. As the therapeutic radiopharmaceutical field continues to expand, dosimetry software has emerged as a crucial tool for optimization of treatment efficacy. This review discusses key features and capabilities that current dosimetry software solutions have or should have in the future.
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