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Formation of Highly Negatively Charged Supported Lipid Bilayers on a Silica Surface: Effects of Ionic Strength and Osmotic Stress.

Langmuir

January 2025

Key Laboratory of Applied Surface and Colloid Chemistry (Ministry of Education), Institute of New Concept Sensors and Molecular Materials, School of Chemistry and Chemical Engineering, Shaanxi Normal University, Xi'an 710062, China.

Solid supported lipid bilayers (SLBs) serve as an excellent platform for biophysical studies. However, the formation of highly negatively charged SLBs on negatively charged surfaces remains a challenge due to electrostatic repulsion. Here, we study the effects of ionic strength and osmotic stress on the formation of highly negatively charged SLBs on the silica surface.

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Topographic Analysis of the Periorbital Region Including Orbicularis Oculi Muscle Based on Ultrasonography Interpretation.

J Cosmet Dermatol

January 2025

Division in Anatomy and Developmental Biology, Department of Oral Biology, Human Identification Research Institute, BK21 FOUR Project, Yonsei University College of Dentistry, Seoul, South Korea.

Objective: Ultrasonographic examination is easy, fast, safe, and used in various fields; however, its application to the facial area has been limited. Complex anatomical structures are mixed within thin, soft tissues in the facial region; therefore, understanding their structural characteristics is crucial. This study aimed to use ultrasonography to obtain information on the layered structure and soft tissue thickness of the eye area around the orbicularis oculi muscle and provide guidance for clinical practice.

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Deep learning has emerged as a powerful tool in medical imaging, particularly for corneal topographic map classification. However, the scarcity of labeled data poses a significant challenge to achieving robust performance. This study investigates the impact of various data augmentation strategies on enhancing the performance of a customized convolutional neural network model for corneal topographic map classification.

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Purpose: To determine whether corneal biomechanical parameters can predict ectasia progression.

Study Design: Retrospective observational study.

Methods: The baseline corneal biomechanical parameters of 64 eyes of 41 young patients (age, < 25 years at the first visit) who were diagnosed with keratoconus (KC) or suspected KC at Osaka University Hospital and followed up for more than two years were reviewed.

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The consequences of climate change, accelerated by anthropogenic activities, have different effects on different ecosystems, and the severity of these effects is predicted to increase in the near future. The number of studies investigating how forest ecosystems respond to these changes is increasing. However, there remains a significant gap in research concerning how saproxylic organisms-one of the key contributors to the healthy functioning of these fragile ecosystems-will respond to the consequences of climate change.

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