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Towards the first synthetic eukaryotic cell.
Biosaf Health
December 2024
Frontiers Science Center for Synthetic Biology and Key Laboratory of Systems Bioengineering (Ministry of Education), School of Chemical Engineering and Technology, Tianjin University, Tianjin 300072, China.
With the rapid advance in synthetic biology and the expanding field of synthetic genomics, the realization of a redesigned yeast genome has become an achievable milestone. Multiple eukaryotic chromosomes, meticulously designed and synthesized, are now being systematically integrated to create an entirely synthetic eukaryotic cell. This comprehensive review examines the fundamental design principles and construction strategies, highlighting critical technological breakthroughs in pursuing the first synthetic eukaryotic cell.
View Article and Find Full Text PDFA Multi-Level Approach to Childhood Obesity Prevention and Management: Lessons from Japan and the United States.
Nutrients
February 2025
Department of Family Medicine, East Carolina University, 101 Heart Drive, Greenville, NC 27834, USA.
Background: Childhood obesity is a pressing global public health challenge, marked by significant disparities in prevalence and management across countries. Japan and the United States offer contrasting approaches to addressing this issue, presenting a valuable opportunity for comparative analysis.
Objective: This review examines the effectiveness of public health policies, cultural dietary habits, and lifestyle factors in combating childhood obesity in Japan and the United States.
Prevalence and impact of fertility preservation among young women with breast cancer.
Sci Rep
March 2025
Department of Radiotherapy Oncology, the First Affiliated Hospital of Xi'an Jiaotong University, 277 Yanta West Road, Xi'an, 710061, China.
To observe the current situation of fertility preservation among female breast cancer patients ≤ 40 years old and analyze the related factors which influence the utilization of fertility preservation. A single-center retrospective questionnaire was conducted investigating patients diagnosed with breast cancer attending The First Affiliated Hospital of Xian JiaoTong University between January 2016 and December 2019. The questionnaire was redesigned based on previous similar research and the questions needed in this study.
View Article and Find Full Text PDFIntention to use eight antenatal care model and associated factors among pregnant women who come for antenatal care in Amhara Region Referral Hospitals, Ethiopia.
Heliyon
February 2025
Department of Midwifery, College of Medicine & Health Sciences, Dilla University, Dilla, Ethiopia.
Background: Maternal and perinatal mortality is highly associated with four or fewer antenatal care (ANC) visit. Due to this, WHO develop a new model called minimum of eight antenatal care (ANC8+) contact. This model is used to re-think and re-design the service through context specific expectations.
View Article and Find Full Text PDFRedesigning urban parks for active living in dense urban areas: a remote audit approach.
Int J Environ Health Res
March 2025
School of Advanced Science and Technology, Japan Advanced Institute of Science and Technology, Nomi, Japan.
The widespread use of virtual audits has transformed the assessment of urban design attributes by eliminating the necessity for on-site visits. However, there remains a lack of virtual audit tools specifically designed for evaluating urban parks in dense urban environments. This study aims to (1) adapt the Audit Tool for Activity-friendly Parks in Dense Urban Areas (TAPS) into a remote audit tool (R-TAPS), and (2) evaluate its reliability and validity.
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