The antianaphylactic effect of globulins obtained from human sera of different blood groups of the ABO system on the active and passive anaphylaxis of guinea pigs, and on mast cells destruction was studied. A marked inhibitory action of globulins obtained from human serum of the B (111) blood group on the allergic reactions of the immediate type was shown. Globulins from the 0 (1) group did not possess such action.
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