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A Heuristic Approach to Analysis of the Genetic Susceptibility Profile in Patients Affected by Airway Allergies.
Genes (Basel)
August 2024
Institute for High Performance Computing and Networking (ICAR), National Research Council (CNR), 90100 Palermo, Italy.
Allergic respiratory diseases such as asthma might be considered multifactorial diseases, having a complex pathogenesis that involves environmental factors and the activation of a large set of immune response pathways and mechanisms. In addition, variations in genetic background seem to play a central role. The method developed for the analysis of the complexities, as association rule mining, nowadays may be applied to different research areas including genetic and biological complexities such as atopic airway diseases to identify complex genetic or biological markers and enlighten new diagnostic and therapeutic targets.
View Article and Find Full Text PDFApplying Market Basket Analysis to Determine Complex Coassociations Among Food Allergens in Children With Food Protein-Induced Enterocolitis Syndrome (FPIES).
Health Serv Res Manag Epidemiol
July 2024
Department of Pediatrics, Baylor College of Medicine, Houston, TX, USA.
Background: Food protein-induced enterocolitis syndrome (FPIES) is a non-IgE-mediated food allergy, characterized by delayed onset of repetitive vomiting occurring 1 to 4 h following ingestion of a food allergen. Managing FPIES requires strict avoidance of the food trigger. The concern with FPIES is determining the risk of another FPIES food trigger reaction due to potential coassociations with other foods or food groups.
View Article and Find Full Text PDFClustering long-term health conditions among 67728 people with multimorbidity using electronic health records in Scotland.
PLoS One
December 2023
School of Medicine, University of St Andrews, St Andrews, United Kingdom.
There is still limited understanding of how chronic conditions co-occur in patients with multimorbidity and what are the consequences for patients and the health care system. Most reported clusters of conditions have not considered the demographic characteristics of these patients during the clustering process. The study used data for all registered patients that were resident in Fife or Tayside, Scotland and aged 25 years or more on 1st January 2000 and who were followed up until 31st December 2018.
View Article and Find Full Text PDFAssessment of a Price Index for Hospital Outpatient Department Services Using Commercial Claims Data in Massachusetts.
JAMA Health Forum
April 2023
Massachusetts Health Policy Commission, Boston.
Specific polysubstance use patterns predict relapse among patients entering opioid use disorder treatment.
Drug Alcohol Depend Rep
December 2022
Department of Public Health Sciences, Division of Biostatistics, University of Miami, Office 1023, 1120 NW 14th St, Miami, FL 33136, USA.
Introduction: While polysubstance use has consistently been associated with higher rates of relapse, few studies have examined subgroups with specific combinations and time course of polysubstance use (i.e., polysubstance use patterns).
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