A study was made of the changes in the calorimetric indices of the energy metabolism (heat emission, "direct" thermoproduction and body temperature) in albino rats with adiposity due to overfeeding and ovariectomy. From the age of 4 months an additional feeding of highly caloric food to normal and ovariectomized animals led to a marked and significant gain in weight. There were marked quantitative changes in the calorimetric indices and the reaction of thermoregulation expressed both in a significant reduction of the initial values of thermal emission, heat production and body temperature, and in the chnages of the reactive peculiarities of heat exchange: reduction of heat emission, diminished accretion of heat production and of the rate of restoration of body temperature after functional "cold" test--in comparison with such in normal animals.

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