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The effect of tonsillectomy on clinical manifestations in Familial Mediterranean fever.

Int J Pediatr Otorhinolaryngol

January 2025

Otorhinolaryngology Department, Faculty of Medicine, Menoufia University, Menoufia, Egypt; Medicine and Surgery Program, Menoufia National University, Menoufia, Egypt. Electronic address:

Purpose: Familial Mediterranean fever (FMF) is the most prevalent genetic autoinflammatory disease worldwide. There are several novel advancements in pathophysiology, genetic testing, diagnosis, comorbidities, disease-related damage, and treatment strategies. This study aimed to assess the effect of tonsillectomy on FMF disease severity and activity.

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Background: Adolescents and young adults (AYA) with cystic fibrosis (CF) are at risk for deviating from their daily treatment regimen due to significant time burden, complicated daily therapies, and life stressors. Developing patient-centric, effective, engaging, and practical behavioral interventions is vital to help sustain therapeutically meaningful self-management.

Objective: This study aimed to devise and refine a patient-centered telecoaching intervention to foster self-management in AYA with CF using a combination of intervention development approaches, including an evidence- and theory-based approach (ie, applying existing theories and research evidence for behavior change) and a target population-centered approach (ie, intervention refinement based on the perspectives and actions of those individuals who will use it).

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Responses of biological characteristics and detoxification enzymes in the fall armyworm to methoxyfenozide stress.

J Econ Entomol

January 2025

Hubei Engineering Technology Center of Forewarning and Management of Agricultural and Forestry Pests, Yangtze University, Jingzhou 434000, PR China.

Methoxyfenozide is an insecticide with a unique mode of action on the insect ecdysone receptor and has been registered for the control of insect pests all over the world. In the present work, Spodoptera frugiperda was exposed to sublethal and lethal concentrations of methoxyfenozide to determine its impact on specific biological traits, metabolic enzyme activity, and the expression of detoxification enzymes. The result showed that 72-h posttreatment with LC50 and LC70 of methoxyfenozide significantly reduced the fecundity (eggs/female) of the F0 generation compared to those of the control group.

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Introduction: Cryptococcal meningitis (CM) combined with intracranial hypertension is associated with a poor prognosis. This study aimed to investigate the therapeutic efficacy and prognostic factors of ventriculoperitoneal (VP) shunt in non-human immunodeficiency virus (HIV) CM patients with intracranial hypertension.

Methodology: A total of 136 non-HIV CM patients with intracranial hypertension treated in our hospital from July 2010 to December 2019 were retrospectively included.

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Introduction: Appropriate antibiotic use requires using the right antibiotic, at the right dose, for the right duration, and at the right time. Drug-resistant diseases cause numerous deaths globally a year, and antibiotic stewardship is a cornerstone in fighting antibiotic resistance. This study focuses on tracking the antibiotic prescribing practices in Palestine and improving future antibiotic prescribing.

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