Objectives: A deficiency in superoxide dismutase (SOD) activity in preeclamptic placentas can lead to an excess of superoxide radicals and may be responsible for the development and the severity of preeclampsia (PE).
Design: Our studies were undertaken in order to determine placental SOD activity and to investigate their association with the development and the severity of PE.
Materials And Methods: The activity of SOD was determined using a spectrophotometric method in 22 placentas from normal term pregnancies (group K), 24 placentas from pregnancies complicated by severe PE (group PE), and 21 placentas from pregnancies complicated by severe PE and intrauterine growth retardation (IUGR) (group PEI).
Results: Mean activity of SOD (MSOD) in 45 preeclamptic placentas 3.89 +/- 1.32 (M +/- SD) was significantly lower (P = 0.008) as compared to MSOD in the group K (6.75 +/- 1.96). MSOD in the PEI group (3.5 +/- 1.29) was significantly lower (P = 0.03) as compared to MSOD in the group K. MSOD in the PE group (4.23 +/- 1.25) was lower than MSOD in the group K, but this difference was not statistically significant (P = 0.11). MSOD in the group PEI was lower as compared to MSOD in the PE group, however this difference was not statistically significant (P = 0.23).
Conclusions: The studies revealed decreased SOD activity in preeclamptic placentas in comparison to normal placentas.
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March 2022
College of Water Conservancy and Civil Engineering, Shandong Agricultural University, Tai'an, Shandong, 271018, China. Electronic address:
Numerous studies have been investigated the toxic effects of silver nanoparticle (Ag-NPs) on algae; however, little attention has been paid to the defense pathways of algae cells to Ag-NPs. In the study, Chlamydomonas reinhardtii (C. reinhardtii) was selected as a model organism to investigate the defense mechanisms to Ag-NPs exposure.
View Article and Find Full Text PDFHospital cultural competency as a systematic organizational intervention: Key findings from the national center for healthcare leadership diversity demonstration project.
Health Care Manage Rev
July 2018
Robert Weech-Maldonado, MBA, PhD, is Professor and L.R. Jordan Endowed Chair, Department of Health Services Administration, University of Alabama at Birmingham. E-mail: Janice L. Dreachslin, PhD, is Professor Emerita of Health Policy and Administration, Penn State Great Valley School of Graduate Professional Studies, Malvern, Pennsylvania. Josué Patien Epané PhD, MBA, is Assistant Professor, Department of Health Care Administration and Policy, School of Community Health Sciences, University of Nevada, Las Vegas. Judith Gail, MSOD, is Owner and Principal, Gail Consulting LLC, Washington, DC. Shivani Gupta, PhD, is Assistant Professor, College for Public Health and Social Justice, Health Management and Policy, Saint Louis University, Missouri. Joyce Anne Wainio, MHA, Vice President, National Center for Healthcare Leadership, Chicago, Illionis.
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Prehepatic portal hypertension worsens the enterohepatic redox balance in thioacetamide-cirrhotic rats.
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December 2008
Surgery I Department, School of Medicine, Complutense University of Madrid, Spain.
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[Influence of heat shock preconditioning on structure and function of mitochondria in gastric mucosa of severely burned animals: experiment with rats].
Zhonghua Yi Xue Za Zhi
February 2008
Center of Burns, First Affiliated Hospital of Nanchang University, Nanchang, China.
Article Synopsis
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