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Certolizumab pegol in severe hidradenitis suppurativa in pregnancy: A case report.
SAGE Open Med Case Rep
January 2025
Section of Dermatology and Venereology, Department of Medicine, University of Verona, Verona, Italy.
Hidradenitis suppurativa is a chronic inflammatory disease of the skin with a suppurative-cicatricial outcome affecting the infundibular component of the pilo-sebaceous unit. The lesions are typically localized in the intertriginous and apocrine gland-rich areas. Hidradenitis suppurativa mainly affects patients at a young age and is very often refractory to conventional medical treatment.
View Article and Find Full Text PDFDissecting Cellulitis Presenting After Hair Restoration Surgery.
Cureus
November 2024
Dermatology, Hospital Universitario "Dr. José Eleuterio González", Nuevo León, MEX.
Dissecting cellulitis (DC) of the scalp is a chronic inflammatory condition marked by neutrophilic cicatricial alopecia, often linked to staphylococcal antigens. This case report details a 34-year-old male with scarring acne who developed DC following follicular unit extraction (FUE) approximately four months prior. Trichoscopic examination revealed brown pigmented dots, erythema, and melicerous crusts.
View Article and Find Full Text PDFLichen Planopilaris Trichoscopy in Caucasian Scalp: A Review.
Skin Appendage Disord
December 2024
Dermatology Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna, Policlinico S. Orsola-Malpighi, Bologna, Italy.
Article Synopsis
- Lichen planopilaris (LPP) is a type of hair loss condition caused by lymphocytic activity, leading to various patterns of permanent hair loss.
- Trichoscopy is a crucial diagnostic tool that helps identify specific signs of LPP, aiding in the diagnosis of different types of lichenoid alopecia.
- Early recognition of trichoscopic signs is essential for timely treatment, which may help prevent the progression of LPP to irreversible scarring.
Graham-Little-Piccardi-Lassueur Syndrome with Mucosal Involvement: A Rare Case.
Int J Trichology
October 2024
Department of Dermatology, Shree Krishna Hospital, Bhaikaka University, Karamsad, Gujarat, India.
Graham-Little-Piccardi-Lassueur syndrome (GLPLS) is a type of lichen planopilaris. It mainly affects females aged 40-60 years. It is characterized by the triad of patchy cicatricial alopecia of the scalp, noncicatricial alopecia of the axilla and groin and a follicular spinous papule on the body, scalp, or both.
View Article and Find Full Text PDFAbnormal placental development induced by repeated cesarean sections: Investigating an animal model of placenta accreta spectrum disorders.
Placenta
December 2024
Department of Obstetrics and Gynecology and Reproductive Medicine, Peking University First Hospital, Beijing, China; Beijing Key Laboratory of Maternal Fetal Medicine of Gestational Diabetes Mellitus, Beijing, China. Electronic address:
Article Synopsis
- Placenta accreta spectrum (PAS) is a serious health issue that can cause severe bleeding after childbirth, often requiring emergency surgery; however, the underlying mechanisms are not well understood due to limitations in animal research.
- In this study, researchers performed multiple cesarean sections on pregnant mice to create a model that mimics the risk factors for PAS, examining various aspects of pregnancy outcomes and placental health.
- Results showed that repeated cesarean sections led to significant complications in pregnancy, including abnormal placental development and fetal issues, indicating that this mouse model closely resembles the clinical features of PAS and can be useful for future research and prevention strategies.
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