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Safety and pharmacokinetics of an intramuscular monoclonal antibody (SB 209763) against respiratory syncytial virus (RSV) in infants and young children at risk for severe RSV disease. | LitMetric
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Safety and pharmacokinetics of an intramuscular monoclonal antibody (SB 209763) against respiratory syncytial virus (RSV) in infants and young children at risk for severe RSV disease.

H C Meissner J R Groothuis W J Rodriguez R C Welliver G Hogg P H Gray R Loh E A Simoes P Sly A K Miller A I Nichols D K Jorkasky D E Everitt K A Thompson

Antimicrob Agents Chemother

Department of Pediatrics, New England Medical Center, Tufts University School of Medicine, Boston, Massachusetts 02111, USA.

Published: May 1999

We conducted a multicenter, double-blind, placebo-controlled, randomized trial of a humanized monoclonal antibody against a respiratory syncytial virus (RSV) fusion protein (SB 209763) to evaluate its safety, pharmacokinetics, and fusion inhibition and neutralization titers. Forty-three infants who were either delivered prematurely (

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC89130PMC
http://dx.doi.org/10.1128/AAC.43.5.1183DOI Listing

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