The kinetics of hemoglobin (Hb) reactions with carbon monoxide were calculated for a number of classical schemes: with one, two, four binding sites and an allosteric scheme with T- and R-conformers. The developed theory predicts the existence of only one relaxation time for every scheme the values of which depends on the velocity constants, saturation degree and the Hb concentration.
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Association between ambient air pollution and outpatient visits of cardiovascular diseases in Zibo, China: a time series analysis.
Front Public Health
January 2025
Department of Epidemiology, School of Public Health, Cheeloo College of Medicine, Shandong University, Jinan, China.
Introduction: Facing Mount Tai in the south and the Yellow River in the north, Zibo District is an important petrochemical base in China. The effect of air pollution on cardiovascular diseases (CVDs) in Zibo was unclear.
Methods: Daily outpatient visits of common CVDs including coronary heart disease (CHD), stroke, and arrhythmia were obtained from 2019 to 2022 in Zibo.
Association between Air Pollutants and Out-of-Hospital Cardiac Arrest: A 5-Year Time Series Analysis.
Eur Heart J Acute Cardiovasc Care
January 2025
Department of Emergency Medicine, The First Affiliated Hospital of Shenzhen University, Shenzhen Second People's Hospital, Shenzhen 518035, Guangdong, China.
Background: We aimed to analyze the yet unclear correlation between air pollutant concentrations (AP) and out-of-hospital cardiac arrest (OHCA) in Shenzhen, China.
Methods: A 5-year time series analysis of all OHCA events reported to the Shenzhen Emergency Center was conducted. Quasi-Poisson regression, controlling for meteorological variables (daily mean relative temperature and humidity) with multivariable fractional polynomial and using Fourier series to adjust for long-term trends and account for periodic patterns, was used to assess the association among particulate matter of 2.
Severity of Repetitive Mild Traumatic Brain Injury Depends on Microglial Heme Oxygenase-1 and Carbon Monoxide.
Eur J Neurosci
January 2025
Department of Anesthesiology & Critical Care, Medical Center-University of Freiburg, Freiburg, Germany.
Traumatic brain injury is one of the most common cerebral incidences worldwide. Repetitive mild traumatic brain injuries occurring, for example, in athletes or victims of abuse, can cause chronic neurodegeneration due to neuroinflammation, in which the crosstalk between reactive astrocytes and activated microglia is crucial for modulating neuronal damage. The inducible enzyme heme oxygenase-1 and its product carbon monoxide are known to be ascribed neuroprotective and anti-inflammatory properties.
View Article and Find Full Text PDFAssessing post-COVID-19 functional recovery in healthcare workers: Insights from the 6-minute walking test and DLCO analysis.
J Infect Public Health
January 2025
Infectious Disease Division, Department of Medicine, Indiana University School of Medicine, Indianapolis, IN, USA; Infectious Disease Unit, Specialty Internal Medicine, Johns Hopkins Aramco Healthcare, Dhahran, Saudi Arabia; Infectious Disease Division, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA. Electronic address:
Introduction: The COVID-19 pandemic has impacted healthcare workers (HCWs) worldwide, necessitating an understanding of its effects on their health and functional capacity. This study utilized the 6-Minute Walk Test (6MWT) and pulmonary function test (PFT) to evaluate post-infection recovery of HCWs, and analyzed the results in relation to comorbidities, symptoms, and healthcare admission.
Methods: HCWs who previously tested positive for SARS-CoV-2 were recruited, and the 6MWT and PFT were conducted.
Cutaneous absorption of methylene chloride is rarely toxic. This case shows that it can lead to carboxyhemoglobinemia. Exposure to methylene chloride should warrant a carboxyhemoglobin check and oxygen support.
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