(-)-(S)-Brevicolline (1) and related beta-carbolines were synthesized using an enantiomerically pure Michael-acceptor synthon (3). Subsequent Pictet-Spengler reaction afforded the tetrahydro-beta-carboline skeleton, which, in turn, was transformed to the beta-carboline by catalytic dehydrogenation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1021/np980492h | DOI Listing |
Publication Analysis
Top Keywords
enantiomerically pure
8
synthesis enantiomerically
4
pure --s-brevicolline
4
--s-brevicolline --s-brevicolline
4
--s-brevicolline beta-carbolines
4
beta-carbolines synthesized
4
synthesized enantiomerically
4
pure michael-acceptor
4
michael-acceptor synthon
4
synthon subsequent
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!