This study examined the postoperative performance of multichannel cochlear implantation in children with severe-to-profound sensorineural hearing loss secondary to large vestibular aqueduct syndrome. Five children between ages 4 and 13 years who had large vestibular aqueducts confirmed by computed tomography scans underwent implantation of a CLARION Multi-Strategy Cochlear Implant between January 1995 and June 1996 at Boys Town National Research Hospital. In addition to preoperative evaluations, they were examined postoperatively with their implants on a battery of open-set speech recognition tests at 3, 6, 12, and 18 months following initial stimulation. Results indicated a noticeable improvement in open-set speech recognition within the first 3 months of implant use compared to preimplant performance with hearing aids. All 5 patients demonstrated substantial benefit from their implants, but there was variation among the children in the rate and amount of improvement in speech recognition skills.
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http://dx.doi.org/10.1177/00034894991080s409 | DOI Listing |
Front Neurol
December 2024
Department of Neurology, The First Hospital of Hebei Medical University, Shijiazhuang, China.
Objective: This study aims to evaluate the short-term efficacy of right-to-left shunt closure in vestibular migraine patients, and compare the efficacy between patent foramen ovale (PFO) closure and pulmonary arteriovenous malformation (PAVM) embolization. Additionally, the study identifies factors related to surgical outcomes.
Methods: Forty-one patients with vestibular migraine and medium to large right-to-left shunts underwent surgery: PFO closure, PAVM embolization, or both.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi
January 2025
This study aimed to compare the effects of cochlear implantation(CI) on vestibular function in patients with large vestibular aqueduct syndrome(LVAS) and in patients with extremely severe deafness with normal inner ear structure. A total of 28 LVAS patients and 28 patients with normal inner ear structure who suffered from extremely severe deafness were selected. The parameters of caloric tests, bone conduction evoked cervical vestibular-evoked myogenic potentials(cVEMP), bone conduction evoked ocular vestibular-evoked myogenic potentials(oVEMP) and video head impulse tests(v-HIT) were compared between the two groups before and after CI.
View Article and Find Full Text PDFBMC Geriatr
December 2024
Department of Ophthalmology, Juntendo Tokyo Koto Geriatric Medical Center, Shinsuna 3-3- 20, Koto-ku, Tokyo, 136-0075, Japan.
Background: Dizziness and unstable gait with resultant falls are common symptoms among the older adults. Most of studies have focused on statistical analysis regarding single factor related to dizziness and unstable gait. On the other hand, there are very few comprehensive studies using a large number of patients except several review papers.
View Article and Find Full Text PDFAnn Anat
December 2024
Department of Urology, Graduate School of Medicine and Dentistry, Hiroshima University School of Medicine, Hiroshima, Japan.
Background: There is little information about when and how cavernosal sinusoidal endothelia develop in the external genitalia of fetuses.
Methods: We examined histological sections of erectile tissue in 37 human fetuses (25 males and 12 females) whose gestational age (GA) ranged from 8 to 40 weeks.
Results: The sinusoidal lumen was filled with blood in the glans of the penis and clitoris at a GA of 10-11 weeks, and in the corpus spongiosum at a GA of 15-16 weeks.
NAR Mol Med
October 2024
Department of Biology, Tufts University, 200 Boston Ave., Medford, MA 02155, USA.
H-DNA is an intramolecular DNA triplex formed by homopurine/homopyrimidine mirror repeats. Since its discovery, the field has advanced from characterizing the structure to discovering its existence and role . H-DNA interacts with cellular machinery in unique ways, stalling DNA and RNA polymerases and causing genome instability.
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