Comparison was made of the effectiveness of cerebellar cortical and nuclear stimulation in reducing paroxysmal activity induced in cats by parenteral penicillin administration. Vermal cortical and fastigial nuclear stimulation at high frequencies (100 Hz) were both effective in reducing the number and duration of paroxysmal events while the effects of dentate nucleus stimulation were found to be more variable. It was suggested that effective seizure inhibition appeared to be associated with increased fastigial output and resultant reticular excitation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/0361-9230(76)90088-5 | DOI Listing |
Publication Analysis
Top Keywords
nuclear stimulation
12
cerebellar nuclear
4
stimulation
4
stimulation generalized
4
generalized penicillin
4
penicillin epilepsy
4
epilepsy comparison
4
comparison effectiveness
4
effectiveness cerebellar
4
cerebellar cortical
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!