It is reported on the casuistics of a 23-year-old Lebanese who since his eighth year suffered from joint swellings and occasional attacks of jaundice. By the proof of false forms of erythrocytes and by the haemoglobin electrophoresis a homozygous sickle cell disease could be ascertained. Peculiarities of the clinical picture were among others changes of the bones of high degree (osteolyses of vertebral bodies, of the head of the right humerus and the heads of the two femurs) was well as of the knee-joints in form of ankyloses.
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