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Topographical Mapping of Metabolic Abnormalities in Multiple Sclerosis using Rapid Echo-less 3D-MR Spectroscopic Imaging at 7T.
Neuroimage
January 2025
High-Field MR Center, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria; Christian Doppler Laboratory for MR Imaging Biomarkers (BIOMAK), Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria.
Objectives: To assess topographical patterns of metabolic abnormalities in the cerebrum of multiple sclerosis (MS) patients and their relationship to clinical disability using rapid echo-less 3D-MR spectroscopic imaging (MRSI) at 7T.
Materials And Methods: This study included 26 MS patients (13 women; median age 34) and 13 age- and sex-matched healthy controls (7 women; median age 33). Metabolic maps were obtained using echo-less 3D-MRSI at 7T with a 64 × 64 × 33 matrix and a nominal voxel size of 3.
Prophylactic HPV vaccination in HPV-related gynecologic cancers: European Society of Gynecological Oncology (ESGO) prevention committee opinion.
Int J Gynaecol Obstet
December 2024
Department of Gynecology and Obstetrics, Comprehensive Cancer Center, Medical University of Vienna, Austria.
Many clinicians recommend that patients diagnosed with HPV-related gynecologic cancers receive prophylactic HPV vaccination at the time of cancer diagnosis or after cancer treatment. In view of the large use of such practice, we aimed to assess the literature evidence supporting the use of prophylactic HPV vaccines after diagnosis or treatment of HPV-related gynecologic cancers. Women who develop HPV-related cervical, vaginal, and vulvar cancers represent a subgroup of patients who may be particularly sensitive to HPV infection and re-acquire infections.
View Article and Find Full Text PDFPerceived Psychological and Physical Health as Predictors of Mortality and Quality of Life in Patients with Lymphedema: A Prospective Study Spanning Almost Two Decades.
Int J Behav Med
December 2024
Lymphatic Clinic, General Hospital Wolfsberg, Wolfsberg, Austria.
Background: How does living with a chronic disease of the lymphatic system affect quality of life and mortality? Lymphedema is a chronic disease mostly affecting women and research is sparse. To this date, longitudinal studies evaluating biopsychosocial predictors for mortality and quality of life in lymphedema are largely missing. This study aims to identify possible predictors and could open innovative ways for treatment options.
View Article and Find Full Text PDFComparable postoperative outcomes in patients treated with either open or arthroscopic trochleoplasty for patella dysplasia.
Knee Surg Relat Res
December 2024
Department of Orthopaedics Surgery, AUVA Trauma Center Klagenfurt, Waidmannsdorferstraße 35, 9020, Klagenfurt Am Wörthersee, Austria.
Background: The aim of this study was to compare the clinical and radiologic results of the arthroscopic and the open trochleoplasty techniques.
Methods: A total of 83 trochleoplasties in 83 patients were performed between 2014 and 2021 in one institution. Surgical indications for trochleoplasty were recurrent patellofemoral instability and a lateral trochlear inclination angle (LTI) ≤ 11˚ and a trochlear depth ≤ 6 mm.
Chronic rhinosinusitis and asthma: epidemiology, pathophysiology, morbidity, treatment.
Curr Opin Otolaryngol Head Neck Surg
February 2025
Department of Otolaryngology- Head and Neck Surgery, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.
Article Synopsis
- The review discusses the growing connection between asthma and chronic rhinosinusitis, especially with the increased use of biologics in treatment.
- It explores the epidemiology, pathophysiology, and treatment options for both conditions, emphasizing their interdependencies.
- The main goal is to encourage physicians to consider both diseases in their treatment approach rather than focusing on only one.
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