On the basis of the concepts presented in Note I, the effects of excluding the duodenum from the digestive circuit are examined. In practice, the effects are reflected in disturbances to intestinal canalization with consequent post-prandial syndromes, and to the digestion and absorption of foods (deficiency syndromes). Over and above histological, biological and biochemical findings, the severe pathology affecting the entire digestive function brought on by the elimination of the manifold, complex activities of the "duodenal laboratory" were confirmed clinically.
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