Samples are drawn from hemophiliacs to retrieve plasma and serum for testing and storage. The samples for testing are tested and the results compiled using a database computer program. The samples for storage are coded and stored at -70 degrees C under controlled conditions. The location of the samples is then entered into the database computer program. The results of the tests, or the stored sample location, can be easily retrieved using the computer.
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Clin Exp Dent Res
February 2025
Department of Dental Research Cell, Dr. D. Y. Patil Dental College and Hospital, Dr. D. Y. Patil Vidyapeeth, Pune, India.
Objectives: Given the complexity of temporomandibular joint disorders (TMDs) and their overlapping symptoms with other conditions, an accurate diagnosis necessitates a thorough examination, which can be time-consuming and resource-intensive. Consequently, innovative diagnostic tools are required to increase TMD diagnosis efficiency and precision. Therefore, the purpose of this umbrella review was to examine the existing evidence about the usefulness of artificial intelligence (AI) in TMD diagnosis.
View Article and Find Full Text PDFFront Immunol
March 2025
Department of Orthopedics, The Second Affiliated Hospital of Nanchang University, Nanchang, Jiangxi, China.
Background: Osteosarcoma, an aggressive bone malignancy predominantly affecting children and adolescents, presents significant therapeutic challenges with a 5-year survival rate below 30% in metastatic cases. T-cell exhaustion, characterized by the overexpression of immune checkpoint molecules, contributes to osteosarcoma progression and immune evasion. Although targeting these inhibitory pathways has shown potential in restoring T-cell activity, the molecular regulators of T-cell depletion in osteosarcoma are poorly understood.
View Article and Find Full Text PDFIran J Pharm Res
December 2024
College of Traditional Chinese Medicine, Hebei North University, Zhangjiakou City, 075000, China.
Background: Herbal compounds sourced from various plants are becoming targeted therapies for breast cancer.
Objectives: This study aims to explore the potential of focusing on herbal compounds as targeted therapies for breast cancer using computational techniques.
Methods: A total of 129 herbal compounds linked with breast cancer were identified from the Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform (TCMSP) database.
Hereditas
March 2025
Department of Gastroenterology, Renmin Hospital of Wuhan University, Zhongxiang, Hubei, 431900, China.
Background And Objective: Changweiqing (CWQ) is a Chinese herbal formula for the treatment of the gastrointestinal tract diseases, but its role in the treatment of colorectal cancer (CRC) has not been clarified. This study aimed to explore the molecular mechanism of CWQ in CRC treatment through bioinformatics analysis and network pharmacology.
Methods: Traditional Chinese Medicine Systems Pharmacology Database and Analysis Platform and SwissTargetPrediction database were used to collect the bioactive components of CWQ.
J Transl Med
March 2025
Unit for Data Science and Computing, North-West University, 11 Hofman Street, Potchefstroom, 2520, South Africa.
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