Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Mitochondrial genomes of the European sardine (Sardina pilchardus) reveal Pliocene diversification, extensive gene flow and pervasive purifying selection.
Sci Rep
December 2024
Departamento de Biologia Animal, Faculdade de Ciências, Universidade de Lisboa, Campo Grande, 1749-016, Lisboa, Portugal.
The development of management strategies for the promotion of sustainable fisheries relies on a deep knowledge of ecological and evolutionary processes driving the diversification and genetic variation of marine organisms. Sustainability strategies are especially relevant for marine species such as the European sardine (Sardina pilchardus), a small pelagic fish with high ecological and socioeconomic importance, especially in Southern Europe, whose stock has declined since 2006, possibly due to environmental factors. Here, we generated sequences for 139 mitochondrial genomes from individuals from 19 different geographical locations across most of the species distribution range, which was used to assess genetic diversity, diversification history and genomic signatures of selection.
View Article and Find Full Text PDFThrombosis, Translational Medicine, and Biomarker Research: Moving the Needle.
J Am Heart Assoc
January 2025
Cardiovascular Research Institute Maastricht, Maastricht University Maastricht Netherlands.
Arterial and venous thromboembolism are leading causes of morbidity and death worldwide. Despite significant advances in the diagnosis, prognostication, and treatment of thrombotic diseases over the past 3 decades, the adoption of findings stemming from translational biomarker research in clinical practice remains limited. Biomarkers provide an opportunity to enhance our understanding of pathophysiological processes and optimize treatment strategies.
View Article and Find Full Text PDFThe Effects of Coronavirus Disease-19 Pandemic on Tuberculosis Treatment Uptake and Outcomes in the Fako Division of Cameroon.
Int J Mycobacteriol
October 2024
Department of Public Health and Hygiene, Faculty of Health Sciences, University of Buea, Buea, Cameroon.
Background: Tuberculosis (TB) caused by Mycobacterium tuberculosis is an infectious disease affecting mainly the lungs and persists as the leading cause of death worldwide. With the emergence of coronavirus disease-19 (COVID-19) pandemic, the management and outcome of TB has been greatly affected because of the global shift in attention. This study aims to determine the effects of COVID-19 pandemic on the TB treatment uptake and outcomes in the Fako Division of Cameroon.
View Article and Find Full Text PDFInterventions to reduce burnout in emergency medicine: a national inventory of the Canadian experience to support global implementation of wellness initiatives.
Intern Emerg Med
December 2024
Department of Emergency Medicine, Neuchâtel Cantonal Hospital, Neuchâtel, Switzerland.
Burnout in healthcare workers is a global issue, with Emergency Medicine (EM) particularly impacted. Many countries have tried implementing wellness initiatives to reduce burnout and improve wellness. This paper summarizes interventions implemented in Canada to-date with the aim of supporting the design of wellness interventions in EDs globally.
View Article and Find Full Text PDFPancreatic Cancer: Current Concepts, Trends, and Future Directions.
Turk J Gastroenterol
November 2024
Comprehensive Cancer Center Munich TUM, TUM University Hospital, Klinikum rechts der Isar, Technical University of Munich, Munich, Germany.
Article Synopsis
- - Pancreatic ductal adenocarcinoma (PC) is a highly aggressive cancer with a low survival rate, projected to become the second leading cause of cancer deaths in the coming decades due to its resistance to treatment.
- - Recent advancements in clinical trials have improved patient survival, with new therapeutic strategies emerging, including adjuvant, neoadjuvant, and palliative treatments aimed at extending life expectancy.
- - The role of molecular tumor boards and genetic profiling is highlighted as vital for enhancing treatment options and customizing therapies, especially with the introduction of targeted therapies like KRAS inhibitors, steering future research directions.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!