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Unlabelled: is an emergent fungal pathogen of significant interest for molecular research because of its unique nosocomial persistence, high stress tolerance and common multidrug resistance. To investigate the molecular mechanisms of these or other phenotypes, a handful of CRISPR-Cas9 based allele editing tools have been optimized for . Nonetheless, allele editing in this species remains a significant challenge, and different systems have different advantages and disadvantages.
View Article and Find Full Text PDFUnlabelled: Neurophysiology studies propose that predictive coding is implemented via alpha/beta (8-30 Hz) rhythms that prepare specific pathways to process predicted inputs. This leads to a state of relative inhibition, reducing feedforward gamma (40-90 Hz) rhythms and spiking to predictable inputs. We refer to this model as predictive routing.
View Article and Find Full Text PDFFish waste biorefinery: A novel approach to promote industrial sustainability.
Bioresour Technol
January 2025
Fish Nutrition Lab, Department of Zoology, Government College University Faisalabad, Punjab 38000, Pakistan.
In pursuit of sustainability and resource efficiency, concept of the circular economy has emerged as a promising framework for industries worldwide. The global fish processing industry generates a significant amount of waste, posing environmental challenges and economic inefficiencies. The substantial volume of fish waste generated globally along with its environmental impact highlights the urgent need to adopt sustainable practices.
View Article and Find Full Text PDFEvaluating the Potential of Microdroplet Flow in Two-Phase Biocatalysis: A Systematic Study.
ACS Appl Mater Interfaces
January 2025
Institute of Microtechnology (IMT), Technische Universität Braunschweig, Alte Salzdahlumer Straße 203, DE-38124 Braunschweig, Germany.
Two-phase biocatalysis in batch reactions often suffers from inefficient mass transfer, inconsistent reaction conditions, and enzyme inactivation issues. Microfluidics offer uniform and controlled environments ensuring better reproducibility and enable efficient, parallel processing of many small-scale reactions, making biocatalysis more scalable. In particular, the use of microfluidic droplets can increase the interfacial area between the two phases and can therefore also increase reaction rates.
View Article and Find Full Text PDFAssociation of socio-demographic characteristics, comorbidities, lifestyle habits, and saliva parameters with dental caries in adults with obesity.
Acta Odontol Scand
January 2025
CHU de Bordeaux, Pôle de Médecine et Chirurgie Bucco-Dentaire, F-33000 Bordeaux, France; Univ. Bordeaux, Oral Health Department, F-33000 Bordeaux, France.
Objective: To describe the oral health status of patients with obesity and to explore the socio-demographic characteristics, comorbidities, lifestyle habits (tobacco, alcohol, sweet/acidic diet), and saliva parameters most associated with the dental caries experience. Material and methods: We conducted a cross-sectional analysis of 204 patients' data with obesity attending a therapeutic education programme. Caries experience (number of decayed, missing, and filled teeth [DMFT]), periodontal status, oral hygiene, occlusal tooth wear, masticatory inefficiency, and saliva parameters were recorded.
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