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Transient chaos and periodic structures in a model of neuronal early afterdepolarization.

Chaos

January 2025

Departamento de Física, Universidade Federal de Santa Catarina, Florianópolis 88040-900, Santa Catarina, Brazil.

The presence of chaos is ubiquitous in mathematical models of neuroscience. In experimental neural systems, chaos was convincingly demonstrated in membranes, neurons, and small networks. However, its effects on the brain have long been debated.

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Purpose: Ozurdex is a dexamethasone intravitreal implant approved for the treatment of macular edema secondary to branch or central retinal vein occlusion, non-infectious uveitis affecting the posterior segment of the eye, and diabetic macular edema.

Patients And Methods: We report a case of an accidental injection of the implant into the crystalline lens, successfully managed by surgery afterwards. The case description is supported by Anterior Segment Optical Coherence Tomography (AS-OCT) images.

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Missing pieces in the puzzle of ecology of microbial arsenate reduction.

J Hazard Mater

December 2024

Guangdong Key Laboratory of Integrated Agro-environmental Pollution Control and Management, Institute of Eco-environmental and Soil Sciences, National-Regional Joint Engineering Research Center for Soil Pollution Control and Remediation in South China, Guangdong Academy of Sciences, Guangzhou 510650, China.

Arsenic pollution and its associated health risks have raised widespread concern. Under anaerobic conditions, arsenic mobility and toxicity increase when arsenate [As(V)] is reduced to arsenite [As(III)] by microbes through the cytoplasmic and dissimilatory pathways. However, the relative importance of these two pathways in the environment remains unclear, restricting our ability to effectively predict and regulate the environmental behavior of arsenic.

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Human brain aging is associated with dysregulation of cell type epigenetic identity.

Geroscience

December 2024

Department of Ecology, Evolution, and Marine Biology, Department of Molecular, Cellular, and Cell Biology, Neuroscience Research Institute, University of California, Santa Barbara, CA, 93106, USA.

Significant links between aging and DNA methylation are emerging from recent studies. On the one hand, DNA methylation undergoes changes with age, a process termed as epigenetic drift. On the other hand, DNA methylation serves as a readily accessible and accurate biomarker for aging.

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