The effect of local X-irradiation on the content of trace elements of subcellular fractions (nuclear, mitochondrial) and the blood serum of rats with sarcoma M-1 was studied. It was shown that systematic local irradiation of sarcoma M-1 (single dose--250 R) during the tumour growth promoted zinc redistribution from the nuclei into the mitochondria. In addition, there were revealed statistically significant postirradiation changes in the blood serum Ca content of rats with sarcoma M-1 after one-time local irradiation of the tumour with 1000 R.

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