Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Polyethylene glycol loxenatide protects diabetic kidneys by inhibiting GRP78/PERK/eIF2α pathway, and improves cardiac injury by suppressing TLR4/NF-κB inflammatory pathway.
BMC Cardiovasc Disord
December 2024
Department of Pharmacy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, No.1277 Jiefang Avenue, Wuhan, 430022, China.
Background: Cardiovascular and renal complications of type 2 diabetes are the main causes of death in diabetic patients. Clinical studies have found that polyethylene glycol loxenatide (PEG-Loxe), a GLP-1 analog widely used to treat type 2 diabetes, boosts renal and cardiac functions in diabetic patients. However, its mechanism of action remains to be elucidated.
View Article and Find Full Text PDFClinical characteristics and booster vaccine effectiveness of the Omicron variant.
BMC Infect Dis
November 2024
Beijing Chest Hospital, Capital Medical University, Beijing, 101149, China.
Article Synopsis
- The study analyzed the characteristics and outcomes of COVID-19 patients during a Beijing Omicron outbreak, focusing on the impact of vaccination status on clinical severity and survival rates.
- Data was collected from 1495 cases, showing that vaccination, especially booster shots, significantly reduced disease severity and increased survival time compared to non-vaccinated individuals.
- Results indicated that elderly patients with pre-existing health conditions had a higher risk of severe illness and death, highlighting the importance of vaccination in this vulnerable population.
Implementation of Virtual Reality Pain Alleviation Therapeutic into Routine Pediatric Clinical Care: Experiences and Perspectives of Stakeholders.
J Med Ext Real
September 2024
Center for Pediatric Trauma Research, The Abigail Wexner Research Institute, Nationwide Children's Hospital, Columbus, Ohio, USA.
Virtual reality (VR) needs to be implemented in clinical settings to improve pediatric patient care during painful medical procedures. Engaging doctors and nurses to lead the adoption of new clinical techniques can facilitate the transition from research to routine practice. Integrating VR into routine clinical practice could reduce patient pain and anxiety, making medical procedures smoother and more efficient.
View Article and Find Full Text PDFQing-Luo-Yin Eased Adjuvant-Induced Arthritis by Inhibiting SIRT1-Controlled Visfatin Production in White Adipose Tissues.
J Inflamm Res
September 2024
Xin'an Medicine Research Center, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital), Wuhu, 241000, People's Republic of China.
Article Synopsis
- The study explored how the herbal formula Qing-Luo-Yin (QLY) affects SIRT1, a protein that regulates metabolism and immune responses, in a rat model of arthritis.
- Treatment with QLY showed a significant reduction in fat in the liver and white adipose tissues of the rats, along with improved joint conditions and altered expression of certain SIRT1-related proteins.
- The research concluded that inhibiting SIRT1 in adipose tissue helps reduce visfatin production in arthritis, which in turn may lessen inflammation, marking a possible anti-rheumatic mechanism of QLY that operates independently of immune regulation.
Importance of Prefabrication to Easing Construction Workers' Experience of Mental Health Stressors.
Int J Environ Res Public Health
September 2024
School of Built Environment, The University of New South Wales, Sydney, NSW 2052, Australia.
Construction is widely acknowledged for its socioeconomic contributions, although it is also always considered as a dangerous and incident-prone industry. As a new method of working, prefabrication presents better work environments and other benefits that can potentially improve the safety and mental health of construction workers. This study compares the extent of stressors in traditional and prefabricated construction.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!