Eliminating from physiologic circulation a significant amount of unnecessary perfluorocarbons (PFC) is advantageous since little is known about long-term effects of PFC in the circulatory system. The basic circuitry, cell-washer, mechanical manipulations, and overall concept revealed that a significant amount of PFC can be retrieved and estimated in volume and compared to initial volumes. A method of separating a certain PFC blood substitute from blood following laboratory cardiopulmonary bypass is described.
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