[On the angio-architecture of intramuscularly implanted Yoshida-sarcoma in untreated and lithium carmine-treated rats (author's transl)].

Investigations were made on the angio-architecture of intramuscularily implanted Yoshida-sarcomas in untreated Wistar-rats and in animals treated with lithium carmine. The injected quantity of lithium carmine led to RES-activation according to the data in the literature. The presentation of the vessels was made by corrosion technique using the synthetic material KALLOCRYL after rinsing the vessels with the proper ester. The pre-existent vessels in the surrounding of the tumor showed an adaptation the expansive growth of the tumor. After starting the experiment the tumor-owned vessels showed an increasing tendency to grow out. The vessels of the treated animals rected in a more regularly and orientated course than those of the untreated animals. In the following time vascularisation in the untreated animals was considerably decreasing, whereas a clear vascularisation was evident in the treated animals until the end of the study. These different findings may be the expression of a local vascular reaction in the implanted tumor following RES-activation induced by lithium carmine.