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Optimizing the regenerative potential of vaginal fibroblasts: The role of autologous platelet-rich plasma and hyaluronic acid in vitro.
Maturitas
January 2025
Faculty of Medicine, Geneva University, 1205 Geneva, Switzerland; Department of Pediatrics, Gynecology and Obstetrics, Division of Gynecology, Urogynecology Unit, Geneva University Hospitals, Geneva, Switzerland. Electronic address:
Objective: Many postmenopausal women suffering from vulvovaginal atrophy are looking for non-hormonal treatments. Platelet-rich plasma (PRP) therapy has emerged as a novel and promising approach for gynecological applications. PRP is an autologous blood product rich in growth factors used to stimulate tissue regeneration.
View Article and Find Full Text PDFThe Management of Iatrogenic Ureterovaginal Fistula in a Resource-Limited Setting: A 12-Year Experience at Four Fistula Surgery Centers in Uganda.
Cureus
December 2024
Obstetrics and Gynecology, Mbarara University of Science and Technology, Mbarara, UGA.
Background Ureterovaginal fistulae usually follow iatrogenic injury to the ureter during pelvic surgery. This manifests as urine incontinence and results in serious psychosocial effects on women. Ureterovaginal fistulae unlike vesicovaginal fistulae present challenges in diagnosis and management especially in resource-constrained settings.
View Article and Find Full Text PDFFistulae Secondary to Vaginal Pessary Use for Pelvic Organ Prolapse: A Systematic Review.
Int Urogynecol J
January 2025
Department of Obstetrics & Gynaecology, Norfolk & Norwich University Hospitals NHS Foundation Trust, Norwich, UK.
Introduction And Hypothesis: Urogenital and rectovaginal fistulae are rare complications of pessary use for pelvic organ prolapse (POP). This systematic review investigates the prevalence of these complications in patients using pessary for POP, potential risk factors and approaches to their investigation and management.
Methods: All studies in English reporting urogenital or rectovaginal fistulae secondary to pessaries for POP were eligible for inclusion.
A road map through the multi-faceted world of female genital cosmetic surgical techniques.
Int J Gynaecol Obstet
January 2025
Obstetrics and Gynecology Unit, IRCCS San Raffaele Scientific Institute, Vita-Salute San Raffaele University, Milan, Italy.
The demand for female genital cosmetic surgery (FGCS) has significantly increased in recent years for two reasons: the advancement of surgical operations and the increased attention to women's esthetic and sexual well-being. Three authors independently analyzed different databases up to April 1, 2024. They selected the relevant data according to inclusion and exclusion criteria.
View Article and Find Full Text PDFAbdominal wound dehiscence after appendectomy during pregnancy treated by negative pressure wound therapy with subsequent vaginal delivery: A case report and literature review.
Int J Gynaecol Obstet
January 2025
Department of Obstetrics and Gynecology, Third Faculty of Medicine, Charles University and University Hospital Kralovske Vinohrady, Prague 10, Czech Republic.
Negative pressure wound therapy (NPWT) is a very effective method in the treatment of dehiscent, infected, and non-healing wounds. Difficult wound healing occurs especially in late pregnancy due to the rapid enlargement of the uterus and the constantly increasing tension of the entire abdominal wall. In cases of dehiscence of the surgical wound during pregnancy, proper subsequent treatment is needed, where it is necessary to consider the safety of the mother as well as the fetus.
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