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Medical Ultrasound Application Beyond Diagnosis: Insights From Ultrasound Sensing and Biological Response.
Biotechnol J
December 2024
Department of Ultrasound Medicine, Tangdu Hospital, Fourth Military Medical University, Xi'an, Shaanxi, China.
Ultrasound (US) can easily penetrate media with excellent spatial precision corresponding to its wavelength. Naturally, US plays a pivotal role in the echolocation abilities of certain mammals such as bats and dolphins. In addition, medical US generated by transducers interact with tissues via delivering ultrasonic energy in the modes of heat generation, exertion of acoustic radiation force (ARF), and acoustic cavitation.
View Article and Find Full Text PDF[Preparation and methodological analysis of chitosan-based ultrasound-coupled hydrogel pads].
Sheng Wu Gong Cheng Xue Bao
December 2024
The College of Life Sciences, Northwest University, Xi'an 710069, Shaanxi, China.
This study aims to optimize the process for preparing chitosan-based ultrasound-coupled hydrogel pads and investigate their application potential in ultrasonography. Chitosan, 2-acrylamido-2-methylpropanesulfonic acid, and N-isopropylacrylamide were used as the main materials to prepare chitosan-based ultrasound-coupled hydrogel pads. The free-radical polymerization conditions were optimized by a three-factor, three-level orthogonal test with the tensile strength and ultrasound image quality of the hydrogel pads as evaluation indicators.
View Article and Find Full Text PDFClinical Maternal and Neonatal Features in COVID-19 Infected Pregnancies in Tianjin, China.
Int J Gen Med
December 2024
Department of Obstetrics and Gynecology, Tianjin First Central Hospital, Nankai University, Tianjin, 300192, People's Republic of China.
Purpose: Outbreak of COVID-19 caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a global pandemic, leading to over 6 million deaths worldwide. Pregnant women suffer from a higher risk facing the pandemic COVID-19, while their related clinical information is limited.
Methods: The clinical information of SARS-CoV-2 positive (n = 30) and negative pregnant women (n = 134) in Tianjin First Central Hospital (from November 30, 2022, to January 20, 2023) were collected.
Ultrasound-Triggered Nanogel Boosts Chemotherapy and Immunomodulation in Colorectal Cancer.
ACS Appl Mater Interfaces
January 2025
Department of Interventional Ultrasound, PLA General Hospital, Beijing 100853, China.
Chemotherapy is the primary therapy for colorectal cancer. However, its efficacy has been limited by chemoresistance, which is mainly caused by inadequate intratumoral drug accumulation and immunosuppressive microenvironments. To address these limitations, we developed a low-intensity ultrasound (LIU)-controlled and charge-reversible nanogel (R-NG), utilizing conjugated chitosan-polypyrrole polymers linked via thioketal bonds, with TiO absorbed onto its surface.
View Article and Find Full Text PDFImprove anti-biofilm efficacy of ultrasound by modulating the phase transition of exopolysaccharides.
Ultrason Sonochem
January 2025
Department of Sports Medicine, Tongji Hospital, School of Medicine, Tongji University, Shanghai, China. Electronic address:
This study focused on the adverse sonochemical effect of ultrasound on biofilm extracellular polysaccharide and the adaptive biofilm responses for ultrasound resistance. Results showed ultrasound triggered phase transition of polysaccharides within biofilm from solation to gelation, which induced following biofilm viscoelasticity enhancement, consequential failure of biofilm removal and bacteria killing. Introducing additional cationic polysaccharide, 1.
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