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Lymphomas With Primary Gastrointestinal Presentation: A Retrospective Study Covering a Five-Year Period at a Quaternary Care Center in Southern India.
Cureus
December 2024
Department of Histopathology and Cytology, Apollo Cancer Center, Chennai, IND.
Background and objective Lymphomas can involve the gastrointestinal (GI) tract as a primary disease or as a secondary spread of systemic disease. The GI tract is a key site for extranodal lymphomas, with Hodgkin lymphoma (HL) and non-Hodgkin lymphoma (NHL) occurring in this region. This study aimed to analyze the demography, anatomic distribution, histological subtypes, and immunomorphological characteristics of all lymphomas with a primary GI presentation at a quaternary care hospital in southern India.
View Article and Find Full Text PDF[Results of clinical and immunomorphological analysis in chronic post-traumatic uveitis].
Vestn Oftalmol
December 2024
AO Meditsina (Academician Roytberg's Clinic), Moscow, Russia.
Purpose: This study was conducted to identify the group at highest risk for autoimmune inflammation through a comparative analysis among patients with chronic post-traumatic uveitis (CPTU).
Material And Methods: The clinical group included 50 patients (aged 18 to 87 years, mean age 41±2.6 years) with CPTU resulting from penetrating injury, contusion, or intraocular surgery.
Reappraisal of Oncocytic Adenocarcinoma: Unveiling Its Connection to Oncocytic Variants of Salivary Duct Carcinoma and Mucoepidermoid Carcinoma Through ImmunoHisto-Molecular Perspectives.
Am J Surg Pathol
January 2025
Department of Pathology, Institut of Pathologie Multisite, University Hospital of Lyon Sud, Hospices Civils de Lyon.
Oncocytic adenocarcinoma (OC) of the salivary glands is a rare and controversial entity. It was recently reclassified as "salivary carcinoma NOS and emerging entities" in the 2022 WHO classification of head and neck tumors. The lack of specific molecular alterations and its potential affiliation with other salivary gland carcinomas, such as the oncocytic mucoepidermoid carcinomas (OMEC) or the oncocytic subtype of salivary duct carcinomas (OSDC) justified this reclassification.
View Article and Find Full Text PDFINFLAMMATORY FACTORS IN DISSECTION OF THORACIC AORTIC ANEURYSM.
Georgian Med News
October 2024
1Petrovsky National Research Center of Surgery, 119435, Moscow; 4Рeoples' Friendship University of Russia named after Patrice Lumumba (RUDN University), 117198, Moscow, Russia.
Unlabelled: In recent years, the prevalence of thoracic aortic aneurysm has increased, and in most cases this pathological condition is diagnosed accidentally. The aim of the current study was to determine the relationship of clinical, laboratory and morphological data with the presence of aorta wall dissection in patients with thoracic aortic aneurysm to reveal factors associated with aorta dissection.
Materials And Methods: The following data of 109 patients mean aged of 53 years with thoracic aortic aneurysm (43 patients with aortic dissection) were analyzed: presence/absence of arterial hypertension, indicators of general blood analysis and blood biochemistry, immunomorphological characteristics of the expression of Von Willebrand factor.
Article Synopsis
- - The study analyzed changes in the molecular characteristics of podocytes in two kidney conditions: primary focal segmental glomerulosclerosis (pFSGS) and IgA nephropathy (IgAN), using kidney samples from patients and negative controls.
- - Results showed that pFSGS patients had significantly higher protein levels in their urine and distinct alterations in podocytes compared to IgAN and negative controls, including decreased WT1 expression and increased desmin expression.
- - The findings suggest that these alterations may indicate a genomic reprogramming in podocytes and their surrounding cells, which could contribute to the pathogenesis of these kidney diseases.
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