Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
A syndemic approach to the study of Covid-19-related death: a cohort study using UK Biobank data.
J Public Health (Oxf)
December 2024
Norwich Medical School, University of East Anglia, Norwich, UK.
Background: The Covid-19 pandemic showed higher infection, severity and death rates among those living in poorer socioeconomic conditions. We use syndemic theory to guide the analyses to investigate the impact of social adversity and multiple long-term conditions (MLTC) on Covid-19 mortality.
Methods: The study sample comprised 154 725 UK Biobank participants.
CHIME Syndrome in a Child With Homozygous PIGL p.Leu167Pro Variant.
Am J Med Genet A
December 2024
Northwest Thames Regional Genetics Service, Northwick Park & St Mark's Hospitals, London, UK.
CHIME syndrome is a variable condition characterized by ichthyosiform dermatosis, accompanied by intellectual disability, ocular colobomas, ear anomalies, and heart defects. It is an autosomal recessive condition caused by biallelic pathogenic variants in the PIGL gene. Until now, all reports of individuals affected with CHIME syndrome showed the PIGL c.
View Article and Find Full Text PDFEvaluating hippocampal replay without a ground truth.
Elife
November 2024
Institute of Behavioural Neuroscience (IBN), University College London (UCL), London, United Kingdom.
During rest and sleep, memory traces replay in the brain. The dialogue between brain regions during replay is thought to stabilize labile memory traces for long-term storage. However, because replay is an internally driven, spontaneous phenomenon, it does not have a ground truth - an external reference that can validate whether a memory has truly been replayed.
View Article and Find Full Text PDFAcceptability and feasibility of a brief intervention to enhance resilience among young people and their families in India and Kenya.
Glob Ment Health (Camb)
October 2024
African Mental Research and Training Foundation, Nairobi, Kenya.
Enhancing resilience is one way to prevent future mental illnesses and encourage recovery in the face of adversity. To develop and test the acceptability and feasibility (A&F) of a combined family and individual resilience intervention in two rural/semi-rural low-income settings in India and Kenya. We developed a five-session intervention including Life Skills Education (LSE) and a model of family resiliency.
View Article and Find Full Text PDFExternal validation and calibration of risk equations for prediction of diabetic kidney diseases among patients with type 2 diabetes in Taiwan.
Cardiovasc Diabetol
October 2024
Division of Metabolism, Endocrinology and Diabetes, Department of Internal Medicine, University of Michigan Medical School, Ann Arbor, MI, USA.
Article Synopsis
- Most current risk equations for predicting diabetic kidney disease (DKD) are based on outdated data from mostly Caucasian populations, prompting the need to adapt these models using real-world data from Taiwanese type 2 diabetes (T2D) patients.
- The study evaluated three simulation models (UKPDS-OM2, RECODe, and CHIME) for their ability to predict DKD progression, with results indicating that while some showed moderate discrimination, they often underestimated or overestimated risks.
- After recalibrating the equations, the updated RECODe for micro- and macroalbuminuria and the CHIME for renal failure exhibited improved predictions, making them suitable for use in a multi-state
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!