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Effect of junctional reflux on the venous clinical severity score in patients with insufficiency of the great saphenous vein (JURY study).
J Vasc Surg Venous Lymphat Disord
March 2024
Department of Surgery, University of Maryland, Baltimore, MD. Electronic address:
Objective: Effective treatment options are available for chronic venous insufficiency associated with superficial venous reflux. Although many patients with C2 and C3 disease based on the CEAP (Clinical-Etiological-Anatomical-Pathophysiological) classification have combined great saphenous vein (GSV) and saphenofemoral junction (SFJ) reflux, some may not have concomitant SFJ reflux. Several payors have determined that symptom severity in patients without SFJ reflux does not warrant treatment.
View Article and Find Full Text PDFPediatric and Adult Brain Death/Death by Neurologic Criteria Consensus Guideline.
Neurology
December 2023
From the Department of Neurology (D.M.G., C.T.), Boston University Chobanian & Avedisian School of Medicine and Boston Medical Center, MA; Departments of Anesthesiology and Critical Care Medicine, Neurology, and Pediatrics (M.P.K.), Children's Hospital of Philadelphia, Perelman School of Medicine at the University of Pennsylvania; Departments of Neurology and Neurosurgery (A.L.), NYU Langone Medical Center, New York City; Department of Neurology (G.S.G.), University of Kansas Medical Center, Kansas City; Department of Neurology (A.R.-G.), Cleveland Clinic Lerner College of Medicine of the Case Western Reserve University, OH; Departments of Pediatrics and Neurology (S.A.), Loma Linda University School of Medicine, CA; Surgical Affiliates Management Group (M.A.B.), Grand Forks, ND; Department of Neurosurgery (D.F.B.), Baylor College of Medicine, Texas Children's Hospital, Houston; Department of Neurology (L.B.), University of Pennsylvania, Philadelphia; Atlanta VA Medical Center and Department of Radiology and Imaging Science (A.C.), Emory University, GA; Departments of Neurology and Pediatrics (S.P.), Stanford University, Palo Alto, CA; Department of Neurology (M.A.R.), University of Texas Southwestern Medical Center, Dallas; Departments of Critical Care Medicine, Neurology, and Neurosurgery (L.S.), University of Pittsburgh, PA; Department of Anesthesia (R.C.T.), Boston Children's Hospital, MA; Department of Neurology (P.N.V.), Albany Medical College, NY; Department of Neurology (E.W.), Mayo Clinic, Rochester, MN; American Academy of Neurology (A.B., S.R.W.), Minneapolis, MN; and Department of Neurosciences (J.J.H.), Overlook Medical Center, Summit, NJ.
Background And Objectives: The purpose of this guideline is to update the 2010 American Academy of Neurology (AAN) brain death/death by neurologic criteria (BD/DNC) guideline for adults and the 2011 American Academy of Pediatrics, Child Neurology Society, and Society of Critical Care Medicine guideline for infants and children and to clarify the BD/DNC determination process by integrating guidance for adults and children into a single guideline. Updates in this guideline include guidance related to conducting the BD/DNC evaluation in the context of extracorporeal membrane oxygenation, targeted temperature management, and primary infratentorial injury.
Methods: A panel of experts from multiple medical societies developed BD/DNC recommendations.
The Impact of Victim Demeanor on Jurors' Perceptions of a Sexual Harassment Victim.
Violence Against Women
December 2023
Department of Psychology, University of Kentucky, Lexington, Kentucky, USA.
Despite the prevalence of sexual harassment in the workplace, little research has investigated the role of victim demeanor in perceptions of sexual harassment cases. The present study varied whether the victim cried while testifying by using drawings of the victim. Participants were presented with a civil trial summary and asked to make trial-related judgments.
View Article and Find Full Text PDFCanagliflozin impairs T cell effector function via metabolic suppression in autoimmunity.
Cell Metab
July 2023
Institute of Life Science, Swansea University Medical School, Swansea University, Swansea SA2 8PP, UK. Electronic address:
Augmented T cell function leading to host damage in autoimmunity is supported by metabolic dysregulation, making targeting immunometabolism an attractive therapeutic avenue. Canagliflozin, a type 2 diabetes drug, is a sodium glucose co-transporter 2 (SGLT2) inhibitor with known off-target effects on glutamate dehydrogenase and complex I. However, the effects of SGLT2 inhibitors on human T cell function have not been extensively explored.
View Article and Find Full Text PDFCalling for justice with #JusticeforBreonnaTaylor: a case study of hashtag activism in the evolution of the black lives matter movement.
Soc Netw Anal Min
April 2023
Department of Journalism and Digital Communication, University of South Florida, 140 7th Avenue South, St. Petersburg, FL 33701 USA.
Taking a stage-based approach, before and after the release of the 15-h audio recording files of the grand jury's inquiry on the Breonna Taylor case on October 2, 2020, this study examined the #JusticeforBreonnaTaylor Twitter networks. By employing multimethodology, including natural language processing, social network analysis, and qualitative textual analysis, I examined keys connectors of the two Twitter networks and investigated major themes conducting thematic analysis of network discourses and highly associated hashtags with the hashtag #JusticeforBreonnaTaylor. In both networks, several key stakeholders, such as Benjamin Crump, Danial Cameron, and Black women activists were identified as key connectors along with social activists and ordinary participants.
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