Several states are watching how a new pooled loan program works in Maine. It links credit enhancements backed by the state to the pooled borrowings, raising their ratings and lowering borrowing costs for participating hospitals. The program also will help improve access to capital for the state's 40 acute-care hospitals.
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Shifting official development assistance during COVID-19: earmarking, donor concentration and loans.
BMJ Glob Health
November 2024
Department of Health Policy, The London School of Economics and Political Science, London, UK
Context: In contrast to bilateral aid, aid disbursed from multilateral institutions increased significantly at the onset of the COVID-19 pandemic. Yet, at a time when a coherent and effective multilateral response is needed most, the COVID-19 pandemic revealed a shifting landscape of donor agencies that struggle with basic functions, such as cross-national coordination. While multilaterals are uniquely positioned to transcend national priorities and respond to pandemics, functionally we find official development assistance (ODA) from these entities may increasingly mimic the attributes of bilateral aid.
View Article and Find Full Text PDFGlucagon-like peptide-1 receptor agonists and risk of gastrointestinal cancers: A systematic review and meta-analysis of randomized controlled trials.
Pharmacol Res
October 2024
Department of Biomedical Sciences, Humanitas University, Pieve Emanuele, Milan, Italy; IRCCS Humanitas Research Hospital, Rozzano, Milan, Italy. Electronic address:
Background: Glucagon-like peptide-1 receptor agonists (GLP-1 RAs) are commonly used for glucose lowering and weight-loss. However, their association with gastrointestinal cancer remains uncertain. This meta-analysis assesses the risk of gastrointestinal cancer in patients treated with GLP-1 RAs.
View Article and Find Full Text PDFThe Iowa Gambling Task: Men and Women Perform Differently. A Meta-analysis.
Neuropsychol Rev
March 2024
Department of Dynamic and Clinical Psychology, and Health Studies, Sapienza University of Rome, Via degli Apuli, 1, Rome, Italy.
The Iowa Gambling Task (IGT) was designed to assess decision-making under conditions of complexity and uncertainty; it is currently one of the most widely used tests to assess decision-making in both experimental and clinical settings. In the original version of the task, participants are given a loan of play money and four decks of cards and are asked to maximize profits. Although any single card unpredictably yields wins/losses, variations in frequency and size of gains/losses ultimately make two decks more advantageous in the long term.
View Article and Find Full Text PDFRisk of COVID-19 death for people with a pre-existing cancer diagnosis prior to COVID-19-vaccination: A systematic review and meta-analysis.
Int J Cancer
April 2024
The Daffodil Centre, The University of Sydney, a joint venture with Cancer Council NSW, Sydney, Australia.
Article Synopsis
- Previous studies linked cancer diagnoses with increased COVID-19 death risk, but many didn’t differentiate between long-term survivors and those recently diagnosed or treated, nor did they consider age factors.
- The research aimed to provide clearer evidence regarding the risk of COVID-19-related death in individuals with active or recent cancers during the pre-vaccination period, analyzing 39 studies that adjusted for age and gender.
- Results indicated that people with recent cancer diagnoses have a significantly higher risk of dying from COVID-19, especially for those with lung or hematological cancers, with the risk decreasing over time since treatment.
Association between circulating inflammatory biomarkers and functional outcome or perihaematomal oedema after ICH: a systematic review & meta-analysis.
Wellcome Open Res
November 2023
Centre for Clinical Brain Sciences, The University of Edinburgh, Edinburgh, Scotland, UK.
Article Synopsis
- There are no specific medical treatments for intracerebral haemorrhage (ICH), but researchers are exploring the link between inflammatory biomarkers in blood and clinical outcomes or brain inflammation.
- A systematic review of studies revealed that certain biomarkers, including fibrinogen and HMGB1, were associated with worse outcomes (like death or dependency) after ICH.
- The study included 16 papers on blood biomarkers and their relationship to perihaematomal edema (PHO) and clinical results, indicating that higher levels of these biomarkers could predict poorer outcomes in ICH patients.
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