The analysis of the parameters of haemodynamics and gas exchange in connection with the tolerance of physical exercises in 57 patients with chronic ischaemic heart disease treated with Obsidan permitted to distinguish two variants of response to the exercises. The first is characterized by a greater increase of the cardiac output and by a slighter participation of the oxygen utilization coefficient and oxygen pulse in ensuring the oxygen regimen of work. The prescription of Obsidan is rational in the first variant of response to the physical exercises.

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