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An international Delphi consensus statement on metabolic dysfunction-associated fatty liver disease and risk of chronic kidney disease.
Hepatobiliary Surg Nutr
June 2023
MAFLD Research Center, Department of Hepatology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China.
Background: With the rising global prevalence of fatty liver disease related to metabolic dysfunction, the association of this common liver condition with chronic kidney disease (CKD) has become increasingly evident. In 2020, the more inclusive term metabolic dysfunction-associated fatty liver disease (MAFLD) was proposed to replace the term non-alcoholic fatty liver disease (NAFLD). The observed association between MAFLD and CKD and our understanding that CKD can be a consequence of underlying metabolic dysfunction support the notion that individuals with MAFLD are at higher risk of having and developing CKD compared with those without MAFLD.
View Article and Find Full Text PDFValidity of Medical Insurance Guidelines for Orthognathic Surgery.
J Oral Maxillofac Surg
March 2021
Director of Surgical Planning Laboratory, Oral and Maxillofacial Surgery Department, Houston Methodist Hospital, Houston, TX; Professor of Oral and Maxillofacial Surgery, Houston Methodist Academic Institute, Houston, TX; and Professor of Surgery (Oral and Maxillofacial Surgery), Weill-Cornell Medical College, New York, NY. Electronic address:
Purpose: The purpose of this study was to assess the validity of the medical insurance guidelines for orthognathic surgery used by the major American medical insurance companies.
Materials And Methods: This study assessed the validity of the medical insurance guidelines for orthognathic surgery used by Aetna, Anthem Blue Cross Blue Shield (BCBS), Cigna, Humana, and UnitedHealthcare (UHC). To evaluate the validity, we calculated the approval and denial rates of the 5 guidelines when we used them to assess the medical necessity for a control group of carefully selected patients.
A novel panel of short mononucleotide repeats linked to informative polymorphisms enabling effective high volume low cost discrimination between mismatch repair deficient and proficient tumours.
PLoS One
February 2019
Institute of Genetic Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom.
Somatic mutations in mononucleotide repeats are commonly used to assess the mismatch repair status of tumours. Current tests focus on repeats with a length above 15bp, which tend to be somatically more unstable than shorter ones. These longer repeats also have a substantially higher PCR error rate, and tests that use capillary electrophoresis for fragment size analysis often require expert interpretation.
View Article and Find Full Text PDFSpine Degenerative Conditions and Their Treatments: National Trends in the United States of America.
Global Spine J
February 2018
University of Southern California, Los Angeles, CA, USA.
Study Design: Retrospective database study.
Objective: Low back and neck pain are among the top leading causes of disability worldwide. The aim of our study was to report the current trends on spine degenerative disorders and their treatments.
The CEO and chairman of Aetna has a penchant for pulling headline-grabbing moves lately, including a high-profile departure from the industry's leading trade association, America's Health Insurance Plans, and an attempt to acquire another big-five insurer, Humana, then pulling out when the Justice Department opposed it.
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