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Cdr1 in focus: a personal reflection on multidrug transporter research.
FEMS Yeast Res
January 2025
Amity Institute of Integrative Science and Health, Amity University Haryana, Gurugram, 122413, India.
Drug resistance mechanisms in human pathogenic Candida species are constantly evolving. Over time, these species have developed diverse strategies to counter the effects of various drug classes, making them a significant threat to human health. In addition to well-known mechanisms such as drug target modification, overexpression, and chromosome duplication, Candida species have also developed permeability barriers to antifungal drugs through reduced drug import or increased efflux.
View Article and Find Full Text PDFWHO public health laboratories webinar series - an online platform to disseminate testing recommendations and best practices during health emergencies.
Front Public Health
January 2025
Public Health Laboratory Strengthening Unit, WHO Lyon Office, Health Emergencies Programme, World Health Organization, Lyon, France.
Laboratories play a central role in managing public health emergencies. The COVID-19 pandemic imposed unique challenges on global laboratory systems, including testing protocol uncertainties, supply shortages, rapid need for information dissemination, and disruptions to traditional training methods. In response, the WHO established the Public Health Laboratories (PHL) knowledge sharing webinar series whose goals were to respond to the increased demand in up-to-date and reliable information, which WHO is in a unique position to provide.
View Article and Find Full Text PDFDeveloping a Novel Integrative Health Equity and Anti-racism Tool (IHEART) for Pilot Application in a Multicenter Integrative Health Elective for Medical Students and Resident Physicians: A Study Protocol.
Glob Adv Integr Med Health
January 2025
Harvard Medical School, Boston, MA, USA.
Background: This study protocol introduces the Integrative Health Equity and Anti-Racism Tool (IHEART), an innovative instrument designed to infuse equity, diversity, and inclusion (EDI) into Integrative Health (IH) education. Recognizing the gaps in current IH training that fail to address social and systemic inequities adequately, the IHEART is intended to respond to the growing need for inclusivity in IH practices and educational materials. The tool is mainly focused on addressing issues such as accessibility of complementary and integrative health (CIH) therapies, cultural misappropriation, anti-racism, gender diversity, disability justice, trauma-informed care, weight inclusivity, and planetary health, which are currently inconsistently covered in IH training.
View Article and Find Full Text PDFIdentification of emerging harms due to COVID-19 outbreak: a qualitative study in Iran.
BMC Public Health
January 2025
Preventive Medicine and Public Health Research Center, Psychosocial Health Research Institute, Department of Community and Family Medicine, School of Medicine, Iran University of Medical Sciences, Tehran, Iran., Shahid Hemmat Highway, Tehran, P.O Box: 14665-354, 1449614535, Iran.
Introduction: Although COVID-19 has altered various harms and exacerbated the prevalence of some of them, this period has also set the stage for the emergence of new harms. The present study aims to identify the emerging harms resulting from the COVID-19 outbreak in Iran.
Methods: The study was conducted using a qualitative content analysis approach through semi-structured interviews with 21 experts and professors knowledgeable about social harms and COVID-19 consequences who were selected through purposive and theoretical sampling.
Latest revisions to the International Health Regulations will fail to prevent future travel chaos.
BMJ Glob Health
January 2025
Faculty of Health Sciences, Simon Fraser University, Burnaby, Canada.
The poor management of public health risks associated with travel by most countries proved among the most contentious issue areas during the COVID-19 pandemic. Evidence from previous outbreaks suggested travel restrictions were largely unnecessary and counterproductive to timely reporting. This led to initial WHO recommendations against the use of travel restrictions.
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