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Unlabelled: In Latin America, scales have been built to assess Early Child Development (EChD), most of them for direct evaluations. In Chile, the Psychomotor Development Evaluation Scale (EEDP) and the Test of Psychomotor Development (TEPSI) were developed in the 70's and 80's and are still used in different Spanish-speaking countries, but have not been updated or revalidated. In response to the need for a new instrument built in Chile for the evaluation of EChD on a large scale, the Test of Early Learning and Development (TADI-2, for its acronym in Spanish) was built and standardized between 2009 and 2012.

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Article Synopsis
  • - A man in his 80s had squamous cell carcinoma on his left temple that was confirmed through biopsy.
  • - After surgery, he faced complications including bleeding, infection, and a pseudoaneurysm of the superficial temporal artery.
  • - Important takeaways involve the recognition and management of uncommon postoperative complications, highlighting that pseudoaneurysms can develop days to weeks after skin cancer surgery.
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Chronic high-dose testosterone disrupts social cognition and enhances social dominance in male long-Evans rats.

Horm Behav

November 2024

Department of Integrative Anatomical Sciences, Keck School of Medicine of the University of Southern California, Los Angeles, CA 90089, United States of America. Electronic address:

While increased aggression is the most consistent behavioral effect of anabolic androgenic steroid (AAS) abuse, its cause remains unclear. AAS may promote aggression by disrupting social behaviors which maintain dominance hierarchies. To model AAS abuse, we treated male rats with chronic high-dose testosterone and tested social recognition, social learning, and competitive and aggressive dominance.

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Detection of virulent Klebsiella pneumoniae strains causing intestinal and extraintestinal infections during the 80s and 90s in Brazil.

Braz J Microbiol

December 2024

Laboratório Experimental de Patogenicidade de Enterobactérias (LEPE), Departamento de Microbiologia, Imunologia e Parasitologia (DMIP), Universidade Federal de São Paulo (UNIFESP), Escola Paulista de Medicina (EPM), São Paulo, SP, Brazil.

Klebsiella pneumoniae is an important pathogen that causes several human infections, which is currently among the main bacterial species of clinical importance. Given the importance of understanding the characteristics of this pathogen and its evolutionary aspects, in this study, we sought to characterize strains of K. pneumoniae recovered in the 1980s and 1990s in São Paulo, Brazil.

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  • - The collaboration between the authors and Professor Shoenfeld's group began in the late 80s, focusing on the anti-phospholipid syndrome (APS) and its underlying mechanisms.
  • - Their studies identified β2 glycoprotein I (β2GPI)-dependent antibodies as key factors that disrupt endothelial function, which is crucial to APS's development.
  • - Recent research has expanded to explore parallels between APS and COVID-19, enhancing understanding through animal models and further studies on endothelial behavior in both conditions.
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