AI Article Synopsis

  • The study examined how long neonatal gnotobiotic piglets infected with a reovirus-like agent shed the virus, focusing on their fecal viral counts.
  • Fecal viral counts peaked just before or at the start of diarrhea, with most piglets shedding the virus for only 1-2 days post-diarrhea onset.
  • Some infected piglets could shed the virus without showing diarrhea, indicating a link between the presence of the virus and the onset of gastrointestinal illness in piglets.

Article Abstract

Virus shedding patterns of neonatal gnotobiotic piglets infected with the reovirus-like agent of human infantile gastroenteritis were studied. Fecal viral counts were highest before or at the onset of diarrhea. In diarrheic piglets, viral particles were usually observed for only 1-2 days after the onset of diarrhea, and total duration of shedding was 2-6 days. One infected piglet shed virus for 4 days but did not develop diarrhea. The presence of virus at or about the time of illness is consistent with the induction of diarrhea in piglets inoculated with the human reovirus-like agent.

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http://dx.doi.org/10.1159/000149957DOI Listing

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