Objective: To establish the diagnostic criteria, analyze the histological patterns of benign and malignant ureteral and renal pelvic polyps in pediatric patients and discuss the best treatment option based on the final diagnosis.
Methods/results: The literature is reviewed with special reference to the diagnostic and therapeutic aspects of fibroepithelial polyps of the upper urinary tract in pediatric patients. An additional case with benign cytological and radiological findings is described. The patient underwent partial pyeloureteral resection. Histological analysis of the surgical specimen confirmed a fibroepithelial polyp.
Conclusions: We emphasize the importance of adequate preoperative evaluation, precise identification of the base of the lesion for a correct choice of the surgical approach, and the advantages of complete segmental resection and reanastomosis over simple excision of the polyp.
Download full-text PDF |
Source |
---|
J Clin Pathol
January 2025
Harvard Medical School, Boston, Massachusetts, USA
Aims: WNT signalling pathway dysregulation is often a critical early component in colorectal neoplasia, particularly the chromosomal instability pathway. Using two WNT reporters, and , we sought to assess whether these polyps demonstrate predictable expression patterns and if these patterns show diagnostic value.
Methods: We evaluated 23 adenomas (TA), 23 sessile serrated lesions (SSLs), 14 SSL with dysplasia and 38 traditional serrated adenomas (TSA).
Cureus
December 2024
Division of Otolaryngology, Department of Surgery, Nemours Children's Health System, Wilmington, USA.
An epiglottic mass (EM) is rarely found in neonates and poses life-threatening airway complications. We present the case of an infant urgently transferred from Belize via the World Pediatric Project with a lingual EM. The EM was misdiagnosed twice.
View Article and Find Full Text PDFPLoS One
December 2024
Upper Airway Chronic Inflammatory Diseases Laboratory, Korea University College of Medicine, Seoul, Republic of Korea.
Th2 inflammation and epithelial-mesenchymal transition (EMT) play crucial roles in the pathophysiology of chronic rhinosinusitis with nasal polyps (CRSwNP). This study aimed to investigate the hypothesis that MMP-12, produced by M2 macrophages, induces EMT in nasal epithelial cells, thereby contributing to airway inflammation and remodeling in CRSwNP. The expression levels of MMP-12 were measured by RT-PCR in CRS nasal mucosa and THP-1 cells.
View Article and Find Full Text PDFTher Adv Gastrointest Endosc
December 2024
Department of Internal Medicine, Hanoi Medical University, Hanoi, Vietnam.
The utilization of artificial intelligence (AI) in gastrointestinal (GI) endoscopy has witnessed significant progress and promising results in recent years worldwide. From 2019 to 2023, the European Society of Gastrointestinal Endoscopy has released multiple guidelines/consensus with recommendations on integrating AI for detecting and classifying lesions in practical endoscopy. In Vietnam, since 2019, several preliminary studies have been conducted to develop AI algorithms for GI endoscopy, focusing on lesion detection.
View Article and Find Full Text PDFGen Thorac Cardiovasc Surg Cases
December 2024
Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto, 606-8507, Japan.
Background: Lung transplantation is a viable lifesaving option for patients with diffuse pulmonary arteriovenous malformations (AVMs). We present a case of diffuse pulmonary AVMs associated with juvenile polyposis and hereditary hemorrhagic telangiectasia (JP-HHT) that was successfully managed by lung transplantation.
Case Presentation: A 19-year-old woman developed severe hypoxemia due to pulmonary AVMs diagnosed at 4 years of age.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!