Syndromes of schizophrenia and language dysfunction.

J Clin Psychol

Psychology Department, College of William & Mary, Williamsburg, VA 23187-8795, USA.

Published: February 1999

This study investigated the relationship between performance on word association and sentence construction tasks and the three-syndrome model of schizophrenic symptoms. Participants were 70 inpatients with a primary diagnosis of schizophrenia. Each participant was rated on positive and negative symptom scales, and ratings were grouped into three syndromal patterns (Reality Distortion, Psychomotor Poverty, and Disorganization). Among the syndromes, only symptoms of disorganization were significantly related to the ability to construct meaningful sentences using word associations. Results suggest that symptoms of disorganization, length of hospitalization, and premorbid adjustment are dimensions that are related to language disturbance in patients with schizophrenia.

Download full-text PDF

Source
http://dx.doi.org/10.1002/(sici)1097-4679(199902)55:2<233::aid-jclp11>3.0.co;2-gDOI Listing

Publication Analysis

Top Keywords

symptoms disorganization
8
syndromes schizophrenia
4
schizophrenia language
4
language dysfunction
4
dysfunction study
4
study investigated
4
investigated relationship
4
relationship performance
4
performance word
4
word association
4

Similar Publications

CFAP65 is essential for C2a projection integrity in axonemes: implications for organ-specific ciliary dysfunction and infertility.

Cell Mol Life Sci

January 2025

State Key Laboratory of Reproductive Medicine and Offspring Health, Department of Histology and Embryology, School of Basic Medical Sciences, Nanjing Medical University, Nanjing, 211166, China.

Defects in motile cilia and flagella lead to motile ciliopathies, including primary ciliary dyskinesia (PCD), which manifests as multi-organ dysfunction such as hydrocephalus, infertility, and respiratory issues. CFAP65 variants are a common cause of male infertility, but its localization and function have remained unclear. In this study, we systematically evaluated CFAP65's role using Cfap65 knockout mice and human patients with CFAP65 variants.

View Article and Find Full Text PDF

Introduction: Endothelial damage is associated with acute and long-term coronavirus disease 2019 (COVID-19) complications. Proximal nailfold capillaries and nail beds give important clues to microvascular changes associated with endothelial dysfunction.

Objective: We aimed to use dermoscopy to examine the proximal nailfold capillaries and nail bed of COVID-19 patients and identify microvascular changes.

View Article and Find Full Text PDF

Brain-derived neurotrophic factor alterations and cognitive decline in schizophrenia: Implications for early intervention.

World J Psychiatry

January 2025

Department of Digital Anti-aging Healthcare (BK21), Inje University, Gimhae 50834, South Korea.

This manuscript explores the recent study by Cui which assessed the interplay between inflammatory cytokines and brain-derived neurotrophic factor (BDNF) levels in first-episode schizophrenia patients. The study revealed that higher levels of interleukin-6 and tumor necrosis factor-α correlated with reduced BDNF levels and poorer cognitive performance. Schizophrenia is a severe psychiatric disorder impacting approximately 1% of the global population, characterized by positive symptoms (hallucinations and delusions), negative symptoms (diminished motivation and cognitive impairments) and disorganized thoughts and behaviors.

View Article and Find Full Text PDF

The Relationships Between Multidimensional Schizotypy and Metacognitive Beliefs.

Psychol Rep

January 2025

School of Psychology, Faculty of Society and Design, Bond University, Gold Coast, QLD, Australia.

There has been a recent surge in schizotypy and metacognition research. Metacognition is an umbrella term for higher-order thought processes. Here, we focussed on maladaptive metacognitive beliefs, which are beliefs related to one's thought processes and often play an important role in the preponderance of psychological disorders.

View Article and Find Full Text PDF

An unprecedented global outbreak caused by the monkeypox virus (MPXV) prompted the World Health Organization to declare a public health emergency of international concern on July 23, 2022. Therapeutics and vaccines for MPXV are not widely available, necessitating further studies, particularly in drug repurposing area. To this end, the standardization of in vitro infection systems is essential.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!