A novel method to transform the nematode Caenorhabditis elegans is described. DNA coprecipitated with gold particles is shot at worms by means of a helium beam. Transformed worms are either identified by a dominant visible marker or selected by a conditional lethal system.
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http://dx.doi.org/10.1016/s0378-1119(99)00043-8 | DOI Listing |
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