A case of gout and secondary amyloid is described. This rare association is described and the literature is reviewed.
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Introduction Parenteral heparin is widely used as bridging therapy while optimising oral anticoagulation(OAC). Newer Direct-Acting OACs(DOACs) attain therapeutic effect very quickly. We report the use of dabigatran as bridging therapy during warfarin optimization for cardioembolic stroke in two patients who opted to receive warfarin for long-term anticoagulation for secondary stroke prevention.
View Article and Find Full Text PDFCardiovascular events in patients with gout initiating urate-lowering therapy with or without colchicine for flare prophylaxis: a retrospective new-user cohort study using linked primary care, hospitalisation, and mortality data.
Lancet Rheumatol
December 2024
Academic Rheumatology, School of Medicine, Nottingham City Hospital, University of Nottingham, Nottingham, UK; National Institute for Health and Care Research Nottingham Biomedical Research Centre, University of Nottingham, Nottingham, UK.
Background: Initiating urate-lowering therapy can trigger gout flares. Gout flares have been associated with a temporally increased risk of cardiovascular events. Therefore, we aimed to estimate the risk of cardiovascular events in patients with gout initiating urate-lowering therapy with flare prophylaxis using colchicine (the drug recommended for gout flare prohphylaxis by many international societies) compared with no prophylaxis.
View Article and Find Full Text PDFThe pleasantness of foods.
Neurophysiol Clin
December 2024
Centre des Sciences du Goût et de l'Alimentation (CSGA) - UMR CNRS 6265, INRAE 1324, University of Burgundy, L'institut Agro - 9E, Boulevard Jeanne d'Arc - 21000 DIJON, France; University Hospital of Dijon, Bourgogne - Department of Neurology - Clinical Neurophysiology - 14, rue Paul Gaffarel - 21000 DIJON, France. Electronic address:
Food pleasantness is largely based on the palatability of food and is linked to taste. Along with homeostatic and cognitive control, it forms part of the control of food intake (hedonic control), and does not only correspond to the pleasure that can be described of food intake. There are many factors that cause variations in eating pleasantness between individuals, such as age, sex, culture, co-morbidities, treatments, environmental factors or the specific characteristics of foods.
View Article and Find Full Text PDFDiverse impact of topography and cultivation location on the polyphenolic profiles and certain sensory attributes of 'País' heritage wines from the Maule dryland region (Chile).
Food Res Int
December 2024
Departamento de Agroindustria y Enología, Facultad de Ciencias Agronómicas, Universidad de Chile, P.O. Box 1004, Santiago, Chile. Electronic address:
Polyphenols are compounds that have traditionally been related to sensory properties of wines. The synthesis of these secondary metabolites can be influenced by numerous factors, including the edaphoclimatic conditions of the growing area of vines. In this study, the effect of topography and cultivation location on the chemical composition and sensory perception of wines was determined.
View Article and Find Full Text PDFGender-specific relationships between hyperuricemia and idiopathic deep venous thrombosis in the Chinese population: a case‒control study.
Thromb J
November 2024
Department of Endocrinology, Qilu Hospital of Shandong University, No. 107 Cultural West Road, JiNan, 250012, China.
Background: Many studies have indicated that hyperuricemia is positively correlated with secondary deep venous thrombosis (DVT); however, the risk factors for idiopathic DVT based on gender differences, such as serum uric acid (SUA) and hyperuricemia, have not been fully examined.
Objectives: To investigate the association between hyperuricemia and the occurrence of idiopathic lower extremity DVT based on gender differences.
Methods: This was a retrospective analysis of 4299 patients who were hospitalized at the Affiliated Hospital of Qingdao University from January 2012 to October 2021 and who underwent ultrasound of the lower limbs.
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