Microcirculation and blood rheology were studied in 348 patients with tumors of the gastrointestinal tract. Such disorders as increased blood and plasma viscosity, aggregates of erythrocytes and their increased stability of shape were recorded in conjunction with hypo- and dysproteinemia, endogenous intoxication syndrome and microvascular disturbances. Microcirculation significantly improved and endoxemia was alleviated following photomodification of the blood by use of helium-neon laser radiation and application of an original procedure of infusion.
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Theranostics
January 2025
Department of Hematology, Zhujiang Hospital, Southern Medical University, Guangzhou, 510280, China.
Colorectal cancer (CRC) is a leading cause of cancer-related mortality. Epigenetic modifications play a significant role in the progression of CRC. KAT7, a histone acetyltransferase, has an unclear role in CRC.
View Article and Find Full Text PDFFront Oncol
December 2024
Clinic for Gastroenterology and Gastrointestinal Oncology, University Medical Center Göttingen (UMG), Göttingen, Germany.
Pancreatic ductal adenocarcinoma (PDAC) is characterized by its poor prognosis. Traditional Japanese herbal medicine (Kampo), such as Juzentaihoto (a standardized combination of 10 herbal extracts), has shown immune modulatory effects, modulation of microcirculation, and amelioration of fatigue. It is administered to patients to prevent deterioration of cachexia and counteract side effects of chemotherapy.
View Article and Find Full Text PDFJ Chin Med Assoc
December 2024
Department of Life Science, School of Life Science, National Taiwan Normal University, Taipei, Taiwan, ROC.
Background: Sepsis is a systemic inflammatory state associated with acute kidney injury (AKI) and high mortality. However, sepsis-induced AKI cannot be effectively prevented or treated using current antimicrobial therapies and supportive measures. We explored the therapeutic effect of newly developed fructose esters on sepsis-induced AKI (S-AKI).
View Article and Find Full Text PDFWorld J Gastroenterol
November 2024
Department of Infectious Diseases, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325000, Zhejiang Province, China.
In this editorial, we examined a recent article in the that focused on sepsis-associated liver injury (SLI) and its treatment. SLI is a serious complication of sepsis, primarily caused by microcirculatory disturbances, the gut-liver axis, and inflammatory responses. Specific treatment recommendations for SLI are lacking.
View Article and Find Full Text PDFSovrem Tekhnologii Med
November 2024
PhD, Senior Researcher, Laboratory of Optical Coherence Tomography, Institute of Experimental Oncology and Biomedical Technologies; Privolzhsky Research Medical University, 10/1 Minin and Pozharsky Square, Nizhny Novgorod, 603005, Russia.
Unlabelled: The condition of gastrointestinal tract determines in many respects the regenerative capacity and the risk of complications in patients with extensive skin burns. However, the mechanism of developing vascular dysfunction in the colon in the burned individuals has so far been poorly studied. is to study intramural circulatory disorders of the colon using optical coherence tomography angiography (OCTA) and laser Doppler flowmetry (LDF) in different time periods after modeling a thermal burn.
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