A study of the incidence of detection of bacteria of the Citrobacter genus in chronic intestinal diseases with the clinical and bacteriological manifestations of dysbacteriosis indicated that the mentioned conditioned pathogenic bacteria were revealed with the same frequency as bacteria of the Proteus genus which served as the commonly accepted index of intestinal dysbacteriosis. Comparative analysis of the intestinal microbial flora of the patients led to a supposition that bacteria of the Citrobacter genus could be found not only in the associations with other microbes, but also as a definite individual group of bacteria during the infectious disease and antibiotic therapy in case of disturbance of normal intestinal biocenosis; this could occur even in the absence in these patients of the known bacteriological indices of dysbacteriosis, thus becoming one of its manifestations.

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