Craniopharyngiomas generally develop either in the suprasellar region or in both suprasellar and intrasellar regions. We report on a nontypical location of the craniopharyngioma in the pineal region. An 8-year-old boy was admitted to the department of pediatric neurosurgery in a grave condition. An MRI scan of the brain was performed after the neurological examination and revealed a large neoplasm situated in the posterior part of the III ventricle and in the pineal region, measuring 8.5x6.5x5 cm. The size of the tumor and its location meant it was occluding three ventricles, with subsequent hydrocephaly. Total removal of the tumor was carried out. Microscopic investigation of the tissue removed showed the typical structure characteristic for craniopharyngioma of the adamantinomatous type. Results of a consultation 6 months after the operation revealed that the patient was feeling well, attending school regularly and had finished the first semester with excellent results. On control MRI scan no tumor was found.
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http://dx.doi.org/10.1007/s003810050316 | DOI Listing |
PLoS One
January 2025
Laboratory of Developmental Biology, Department of Morphology and Genetics-Paulista Medicine School, Federal University of Sao Paulo (UNIFESP), Sao Paulo, SP, Brazil.
Melatonin is a pineal hormone synthesized exclusively at night, in several organisms. Its action on sperm is of particular interest, since they transfer genetic and epigenetic information to the offspring, including microRNAs, configuring a mechanism of paternal epigenetic inheritance. MicroRNAs are known to participate in a wide variety of mechanisms in basically all cells and tissues, including the brain and the sperm cells, which are known, respectively, to present 70% of all identified microRNAs and to transfer these molecules to the embryo.
View Article and Find Full Text PDFCureus
January 2025
Radiation Oncology, Centre Hospitalier Affilié Universitaire Régional, Trois-Rivieres, CAN.
Papillary tumors of the pineal region (PTPR) are extremely rare malignancies that make up less than 0.1% of primary brain tumors. They are usually treated with surgery and adjuvant tumor bed radiotherapy (RT).
View Article and Find Full Text PDFVitam Horm
January 2025
Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Ciudad Autónoma de Buenos Aires, Argentina; Centro de Estudios Biomédicos Básicos, Aplicados y Desarrollo (CEBBAD), Universidad Maimónides, Ciudad Autónoma de Buenos Aires, Argentina. Electronic address:
Light is the most reliable environmental cue allowing animals to breed successfully when conditions are optimal. In seasonal breeders, photoperiod (length of daylight) information is sensed by the eyes and transmitted to the suprachiasmatic nucleus, the master clock region located in the hypothalamus. This structure has a 24-h firing rhythm involving a cycle of clock protein synthesis and degradation, and provides the timing to synchronize the synthesis and release of melatonin, the chemical signal that transduces the photoperiod information.
View Article and Find Full Text PDFQuant Imaging Med Surg
January 2025
Department of Radiology, Seventh Medical Center of Chinese PLA General Hospital, Beijing, China.
Background: Pineal region tumors encompass a wide range of pathologies, presenting challenges in pre-surgical characterization and exhibiting variable prognostic outcomes across different tumor types. This study aims to identify key imaging features from pre-treatment magnetic resonance imaging (MRI) of pineal region tumors to aid in prognostic analysis.
Methods: We retrospectively enrolled 33 patients with pineal region tumors who underwent pre-treatment imaging at the Seventh Medical Center of the Chinese PLA General Hospital between January 2010 and June 2023.
Naturwissenschaften
January 2025
Programa de Pós-Graduação em Biodiversidade Animal, Universidade Federal de Santa Maria, Av. Roraima 1000, 97105-900, Santa Maria, RS, Brazil.
This paper analyzes the paleoneurology (cranial endocast and maxillary canal) of Massetognathus pascuali, an iconic non-mammaliaform cynodont from the early Late Triassic of South America, using Neutron Tomography. The application of neutron tomography holds the potential for uncovering more refined anatomical and quantitative data. The newly examined cranial endocast shows a forebrain with a tubular shape without an interhemispheric fissure, presence of a pineal body (with a closed parietal foramen), and a marked unossified zone.
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