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Fully-automated segmentation of muscle and inter-/intra-muscular fat from magnetic resonance images of calves and thighs: an open-source workflow in Python.
Skelet Muscle
December 2024
Rehabilitation Sciences Institute, University of Toronto, Toronto, ON, Canada.
Background: INTER- and INTRAmuscular fat (IMF) is elevated in high metabolic states and can promote inflammation. While magnetic resonance imaging (MRI) excels in depicting IMF, the lack of reproducible tools prevents the ability to measure change and track intervention success.
Methods: We detail an open-source fully-automated iterative threshold-seeking algorithm (ITSA) for segmenting IMF from T1-weighted MRI of the calf and thigh within three cohorts (CaMos Hamilton (N = 54), AMBERS (N = 280), OAI (N = 105)) selecting adults 45-85 years of age.
Spatiotemporal patterns and drivers of orchard meadow loss in South Tyrol, Italy.
Sci Rep
December 2024
Institute for Alpine Environment, Eurac Research, Drususallee/Viale Druso 1, Bolzano/Bozen, 39100, Italy.
Orchard meadows, a specific agroforestry system characterised by scattered high-stem fruit trees, are a traditional element of several cultural landscapes in Central Europe and provide important ecosystem services. Since the middle of the 20th century, orchard meadows have drastically declined across Europe. Spatial information on the drivers and patterns of such a decline in several regions in Central Europe is lacking.
View Article and Find Full Text PDFSymptoms Prior to Diagnosis of Multiple Sclerosis in Individuals Younger Than 18 Years.
JAMA Netw Open
December 2024
Department of Epidemiology and Health Care Atlas, Central Research Institute of Ambulatory Health Care, Berlin, Germany.
Importance: A growing body of literature suggests the presence of a prodromal period with nonspecific signs and symptoms before onset of multiple sclerosis (MS).
Objective: To systematically assess diseases and symptoms diagnosed in the 5 years before a first MS- or central nervous system (CNS) demyelinating disease-related diagnostic code in pediatric patients compared with controls without MS and controls with another immune-mediated disorder, juvenile idiopathic arthritis (JIA).
Design, Setting, And Participants: This population-based, matched case-control study included children and adolescents (aged <18 years) in Germany with statutory health insurance from January 2010 to December 2020.
Evolution of Key Factors Influencing Performance Across Phases in Junior Short Sprints.
Sports (Basel)
November 2024
Faculty of Arts and Sciences, Kyoto Institute of Technology, Hashikami-cho, Matsugasaki, Sakyo-ku, Kyoto 606-8585, Japan.
Sprint performance plays a crucial role in various sports. Short sprints vary depending on the size of the court/playing field and on competitive characteristics, but are common in many sports. Although the relationship between age and muscle strength has been explored in short sprints, there is limited understanding of how various physical factors interact, particularly concerning differences in the acceleration phase.
View Article and Find Full Text PDFAnxiety, Depression, and Quality of Life in Women with Breast Cancer and Type 2 Diabetes: A Pilot Study in North Greece.
J Pers Med
December 2024
Nursing Department, International Hellenic University, 57001 Thessaloniki, Greece.
: The incidence of breast cancer, as well as diabetes mellitus (DM), has continuously increased in recent years. The concurrent study of these diseases is particularly important, as there is a strong correlation between them due to hormonal, biochemical, and environmental factors. Moreover, the underlying metabolic dysfunction in this case could affect the treatment of breast cancer, as well as overall survival.
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