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Vertex model with internal dissipation enables sustained flows.
Nat Commun
January 2025
School of Life Sciences, University of Dundee, Dundee, UK.
Complex tissue flows in epithelia are driven by intra- and inter-cellular processes that generate, maintain, and coordinate mechanical forces. There has been growing evidence that cell shape anisotropy, manifested as nematic order, plays an important role in this process. Here we extend an active nematic vertex model by replacing substrate friction with internal viscous dissipation, dominant in epithelia not supported by a substrate or the extracellular matrix, which are found in many early-stage embryos.
View Article and Find Full Text PDFAppropriate surgical management in skin and soft tissue infections.
Curr Opin Infect Dis
January 2025
Department of Surgery, Klinik Donaustadt, Vienna Healthcare Group, Austria.
Purpose Of Review: To present standards and recent technical innovations in the surgical management of skin and soft tissue infections (SSTI).
Recent Findings: SSTI are a frequent cause of presentation in the acute care setting. They can range from simple and uncomplicated to severe and necrotizing infections.
Dementia is a global public health challenge, impacting > 55 million individuals worldwide. However, widespread dissemination of efficacious non-pharmacologic interventions remains limited. A key implementation barrier is workforce preparation and support for healthcare professionals (HPs) and administrators when being trained in, implementing, and sustaining programs.
View Article and Find Full Text PDFExpected profitability, independence, and risk assessment of small farmers in the wave of GM crop collectivization--evidence from Xinjiang and Guangdong.
GM Crops Food
December 2025
Research Center for Chinese Politics, School of Government, Peking University, Beijing, China.
As a longstanding and indispensable part of developing countries, small farmers face challenges brought by the dissemination of GM technology. Despite governments' efforts to promote collective cultivation of GM crops through top-down policies aimed at enhancing small farmers' production efficiency and market competitiveness, actual participation rates among small farmers in many developing countries remain low. This reflects a gap and mismatch between policy design and the actual needs of small farmers.
View Article and Find Full Text PDFEffect of Total and Partial Meal Replacements on Factors Related to Glucose Metabolism: A Systematic Review and Meta-analysis of Randomized Controlled Trials.
Nutr Rev
January 2025
Department on Nutrition, School of Public Health, Shahid Sadoughi University of Medical Sciences, Yazd 8915173149, Iran.
Context: Although some evidence shows the beneficial effects of meal replacements (MRs) on glucose metabolism as one of the main factors of diabetes, there are still no comprehensive findings in this field.
Objective: We investigated the effects of total and partial MRs on fasting blood sugar (FBS), insulin, glycated hemoglobin (HbA1c), and homeostatic model assessment for insulin resistance (HOMA-IR) in this comprehensive study and meta-analysis.
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