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ESO-Based Non-Singular Terminal Filtered Integral Sliding Mode Backstepping Control for Unmanned Surface Vessels.
Sensors (Basel)
January 2025
College of Shipbuilding Engineering, Harbin Engineering University, Harbin 150001, China.
Aiming at the control challenges faced by unmanned surface vessels (USVs) in complex environments, such as nonlinearities, parameter uncertainties, and environmental perturbations, we propose a non-singular terminal integral sliding mode control strategy based on an extended state observer (ESO). The strategy first employs a third-order linear extended state observer to estimate the total disturbances of the USV system, encompassing both external disturbances and internal nonlinearities. Subsequently, a backstepping sliding mode controller based on the Lyapunov theory is designed to generate the steering torque control commands for the USV.
View Article and Find Full Text PDFCharge Reversal of the Uppermost Arginine in Sliding Helix S4-I Affects Gating of Cardiac Sodium Channel.
Int J Mol Sci
January 2025
Almazov National Medical Research Centre, 197341 St. Petersburg, Russia.
Several mutations of the uppermost arginine, R219, in the voltage-sensing sliding helix S4 of cardiac sodium channel Nav1.5 are reported in the ClinVar databases, but the clinical significance of the respective variants is unknown (VUSs). AlphaFold 3 models predicted a significant downshift of S4 in the R219C VUS.
View Article and Find Full Text PDFA Microfluidic-Based Cell-Stretching Culture Device That Allows for Easy Preparation of Slides for Observation with High-Magnification Objective Lenses.
Micromachines (Basel)
January 2025
Department of Chemical and Biological Sciences, Faculty of Science, Japan Women's University, 2-8-1 Mejirodai, Bunkyo, Tokyo 112-8681, Japan.
Microfluidic-based cell-stretching devices are vital for studying the molecular pathways involved in cellular responses to mechanobiological processes. Accurate evaluation of these responses requires detailed observation of cells cultured in this cell-stretching device. This study aimed to develop a method for preparing microscope slides to enable high-magnification imaging of cells in these devices.
View Article and Find Full Text PDFA machine learning based algorithm accurately stages liver disease by quantification of arteries.
Sci Rep
January 2025
Shuguang Hospital, Shanghai University of Traditional Chinese Medicine, 528 Zhangheng Road, Pudong New Area, Shanghai, 201203, China.
A major histologic feature of cirrhosis is the loss of liver architecture with collapse of tissue and vascular changes per unit. We developed qVessel to quantify the arterial density (AD) in liver biopsies with chronic disease of varied etiology and stage. 46 needle liver biopsy samples with chronic hepatitis B (CHB), 48 with primary biliary cholangitis (PBC) and 43 with metabolic dysfunction-associated steatotic liver disease (MASLD) were collected at the Shuguang Hospital.
View Article and Find Full Text PDFMechanical force-induced interlayer sliding in interfacial ferroelectrics.
Nat Commun
January 2025
Key Laboratory of Polar Materials and Devices (Ministry of Education), Shanghai Center of Brain-Inspired Intelligent Materials and Devices, Department of Electronics, East China Normal University, Shanghai, 200241, China.
Moiré superlattices in two-dimensional stacks have attracted worldwide interest due to their unique electronic properties. A typical example is the moiré ferroelectricity, where adjacent moirés exhibit opposite spontaneous polarization that can be switched through interlayer sliding. However, in contrast to ideal regular ferroelectric moiré domains (equilateral triangles) built in most theoretical models, the unavoidable irregular moiré supercells (non-equilateral triangles) induced by external strain fields during the transfer process have been given less attention.
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