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Uncommon Magnetic Ordering in the Quantum Magnet Yb_{3}Ga_{5}O_{12}.
Phys Rev Lett
December 2024
Université Grenoble Alpes, Grenoble INP, CEA, IRIG, PHELIQS, 38000 Grenoble, France.
The antiferromagnetic structure of Yb_{3}Ga_{5}O_{12} is identified by neutron diffraction experiments below the previously known transition at T_{λ}=54 mK. The magnetic propagation vector is found to be k=(1/2,1/2,0), an unusual wave vector in the garnet structure. The associated complex magnetic structure highlights the role of exchange interactions in a nearly isotropic system dominated by dipolar interactions and finds echoes with exotic structures theoretically proposed.
View Article and Find Full Text PDFMRI-Based Circumferential Strain in Boys with Early Duchenne Muscular Dystrophy Cardiomyopathy.
Diagnostics (Basel)
November 2024
Department of Radiology, Stanford University, Palo Alto, CA 94305, USA.
In boys with Duchenne muscular dystrophy (DMD), cardiomyopathy has become the primary cause of death. Although both positive late gadolinium enhancement (LGE) and reduced left ventricular ejection fraction (LVEF) are late findings in a DMD cohort, LV end-systolic circumferential strain at middle wall (E) serves as a biomarker for detecting early impairment in cardiac function associated with DMD. However, E derived from cine Displacement Encoding with Stimulated Echoes (DENSE) has not been quantified in boys with DMD.
View Article and Find Full Text PDFThe heartbeat induces local volumetric compression in the healthy human brain: a 7 T magnetic resonance imaging study on brain tissue pulsations.
Interface Focus
December 2024
Translational Neuroimaging Group, Center for Image Sciences, University Medical Center Utrecht, Utrecht, The Netherlands.
Intracerebral blood volume changes along the cardiac cycle cause volumetric strain in brain tissue, measurable with displacement encoding with stimulated echoes (DENSE) magnetic resonance imaging. Individual volumetric strain maps show compressing and expanding voxels, raising the question whether systolic compressions reflect a physiological phenomenon. In DENSE data from nine healthy volunteers, voxels were grouped into three clusters according to volumetric strain in a tissue mask excluding extracerebral blood vessels and cerebrospinal fluid using a two-stage clustering approach.
View Article and Find Full Text PDFImproving Vessel Visibility and Applying Artificial Intelligence to Autodetect Brain Metastasis for a 3D MR Imaging Sequence Capable of Simultaneous Images with and without Blood Vessel Suppression.
Magn Reson Med Sci
November 2024
Department of Molecular Imaging and Diagnosis, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Fukuoka, Japan.
Article Synopsis
- The study aimed to enhance vessel visibility in MR imaging by adjusting k-space filling techniques and to assess the effectiveness of an AI approach for detecting brain metastases using a method called VISIBLE with compressed sensitivity encoding (CS).
- Three variations of the VISIBLE sequence (Centric, Reversed Centric, and Startup Echo 30) were tested. While the Reversed Centric method produced fewer false positives, all three showed similar sensitivity and specificity for brain metastasis detection.
- The findings indicated that modifying k-space filling improves vessel visibility and reduces false positives, while the AI model proved effective in autonomously detecting brain metastases in the MRI scans.
Effect of Microbubble Size, Composition, and Multiple Sonication Points on Sterile Inflammatory Response in Focused Ultrasound-Mediated Blood-Brain Barrier Opening.
ACS Biomater Sci Eng
December 2024
Biomedical Engineering Program, University of Colorado Boulder, Boulder, Colorado 80303, United States.
Blood-brain barrier opening (BBBO) using focused ultrasound (FUS) and microbubbles (MBs) has emerged as a promising technique for delivering therapeutics to the brain. However, the influence of various FUS and MB parameters on BBBO and subsequent sterile inflammatory response (SIR) remains unclear. In this study, we investigated the effects of MB size and composition, as well as the number of FUS sonication points, on BBBO and SIR in an immunocompetent mouse model.
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