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Multifactorial Induction of a "Scleroderma-Like Pattern" Without Underlying Connective Tissue Disease: Diagnostic and Therapeutic Implications.
ACR Open Rheumatol
January 2025
Madonna delle Grazie Hospital, Matera, Italy.
A 60-year-old man with a significant 20-year history of smoking, averaging approximately 20 cigarettes per day, presented with type 2 diabetes mellitus, hypercholesterolemia, and hypertension. Over the preceding three months, the patient reported recurrent episodes of acrocyanosis and erythema of the hands that were primarily induced by cold exposure. A capillaroscopy conducted in November 2024 revealed a "scleroderma-like pattern" that was characterized by enlarged capillaries, megacapillaries, and a capillary density of fewer than eight capillaries per millimeter.
View Article and Find Full Text PDFAlterations on Nailfold Videocapillaroscopy in Myelodysplastic Syndrome and Onychomycosis in a Female Smoker: Microvascular Dysfunction Without Connective Tissue Disease.
Int J Rheum Dis
December 2024
Department of Rheumatology of Lucania-UOSD of Rheumatology, "Madonna delle Grazie" Hospital, Matera, Italy.
A 58-year-old female smoker diagnosed with myelodysplastic syndrome (MDS) presented with Raynaud's phenomenon and a "scleroderma-like" pattern on nailfold capillaroscopy. The capillaroscopic abnormalities were observed across all fingers, including those without clinical manifestations of onychomycosis. Over a two-year follow-up, there was no evidence of clinical or serological progression toward a connective tissue disease, particularly systemic sclerosis.
View Article and Find Full Text PDFNailfold microscopy in adult-onset dermatomyositis in association with myositis antibodies.
Arch Dermatol Res
November 2024
Center for Dermatology, Rutgers Robert Wood Johnson Medical School, Somerset, NJ, USA.
Dermatomyositis (DM) is an immune mediated inflammatory disease classically associated with muscular and cutaneous involvement. Existing studies have suggested characteristic nailfold findings may be observed in DM, indicating a potential role for nailfold microscopic examination in the diagnosis of DM. To that end, we performed a systematic review of literature pertaining to nailfold microscopic, capillaroscopic, and dermoscopic findings observed in patients with DM, with a secondary review of the association of nailfold microscopic findings with myositis-specific antibody (MSA) and myositis-associated antibody (MAA) status.
View Article and Find Full Text PDFNailfold videocapillaroscopy abnormalities and vascular manifestations in Behçet's syndrome.
Clin Exp Rheumatol
October 2024
Systemic Autoimmune Diseases Unit, Vall d'Hebron General Hospital, Universitat Autònoma de Barcelona, Spain.
Article Synopsis
- The study aimed to assess microcirculation abnormalities in patients with Behçet's Syndrome (BS) and their link to vascular issues using nailfold videocapillaroscopy (NVC).
- Out of 65 patients, 36.9% showed vascular involvement, with NVC revealing abnormalities like tortuous capillaries and microhaemorrhages in nearly half of the participants.
- Significant correlations were found between specific NVC abnormalities and vascular complications, indicating that NVC could be useful for early identification of patients at risk for vascular events.
Video-Capillaroscopic Observation of Lymph Flow Following Lymphaticovenular Anastomosis.
Microsurgery
October 2024
Department of Plastic and Reconstructive Surgery, National Center for Global Health and Medicine, Tokyo, Japan.
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