Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1103/PhysRevLett.72.1972 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Observation of a rare beta decay of the charmed baryon with a Graph Neural Network.
Nat Commun
January 2025
The beta decay of the lightest charmed baryon provides unique insights into the fundamental mechanism of strong and electro-weak interactions, serving as a testbed for investigating non-perturbative quantum chromodynamics and constraining the Cabibbo-Kobayashi-Maskawa (CKM) matrix parameters. This article presents the first observation of the Cabibbo-suppressed decay , utilizing 4.5 fb of electron-positron annihilation data collected with the BESIII detector.
View Article and Find Full Text PDFThe Colorado Heart Failure Acuity Risk Model: A Mortality Model for Waitlisted Cardiac Transplant Patients.
JACC Adv
January 2025
Department of Surgery, Division of Transplant Surgery, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
Background: Currently, there is no mathematical model used nationally to determine the medical urgency of patients on the heart transplant waitlist in the United States. While the current organ distribution system accounts for many patient factors, a truly objective model is needed to more reliably stratify patients by their medical acuity.
Objectives: The aim of the study was to develop risk scores (Colorado Heart failure Acuity Risk Model [CHARM] score) to predict mortality in adults waitlisted for heart transplant.
Elucidating acquired PARP inhibitor resistance in advanced prostate cancer.
Cancer Cell
December 2024
The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, London, UK. Electronic address:
Article Synopsis
- - PARP inhibitors show promise in treating castration-resistant prostate cancer (CRPC) with homologous recombination repair (HRR) defects, but the reasons behind resistance are not completely understood.
- - A study from the TOPARP-B trial found that 79% of BRCA2/PALB2-mutated tumors exhibited reversion mutations at the end of treatment, with many related to POLQ-mediated DNA repair mechanisms.
- - In cases of BRCA2 homozygous deletions, rare subclones lacking the BRCA2 deletion are selected for after PARP inhibitor treatment, indicating the necessity for restored HRR function in developing resistance.
Feasibility and acceptability of tailored sexual assault prevention in the US Air Force.
Pilot Feasibility Stud
November 2024
Headquarters Air Force A1Z (Integrated Resilience Directorate), Arlington, VA, USA.
Background: Sexual assault prevention is a priority for the military and is likely to be most effective when tailored to specific needs and individual experiences. Technology advances make it possible to integrate individualized programming into group education settings common to military training, but this approach is not without potential challenges. Prior to implementing and evaluating a novel prevention program, it is critical to conduct a feasibility study to assess the extent to which the program can be successfully implemented, is acceptable to participants, and can be rigorously evaluated.
View Article and Find Full Text PDFPost-Cardiac arrest outcome prediction using machine learning: A systematic review and meta-analysis.
Int J Med Inform
January 2025
BioMedical Machine Learning Lab, School of Biomedical Engineering, UNSW Sydney, Randwick, NSW 2052, Australia.
Background: Early and reliable prognostication in post-cardiac arrest patients remains challenging, with various factors linked to return of spontaneous circulation (ROSC), survival, and neurological results. Machine learning and deep learning models show promise in improving these predictions. This systematic review and meta-analysis evaluates how effective these approaches are in predicting clinical outcomes at different time points using structured data.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!