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Lymphangioma circumscriptum, one of the common forms of lymphangioma, can be either congenital or acquired. Various acquired conditions can lead to its causation and one of the causes might be untreated hidradenitis suppurativa. So, this report highlights the need of early interventions for hidradenitis suppurativa as lymphangioma circumscriptum can be one of its consequences later in life.
View Article and Find Full Text PDFBiological implications of decoding the extracellular matrix of vulva cancer.
Oncol Rep
February 2025
Center for Cancer Biomarkers and Gade Laboratory for Pathology, Institute of Clinical Medicine, University of Bergen, 5021 Bergen, Norway.
The present review aimed to elucidate the roles of extracellular matrix (ECM) components in the progression of vulvar squamous cell carcinoma (VSCC) and explore potential therapeutic avenues for this type of malignancy. This exploration holds promise for identifying precise molecular targets within the ECM milieu, thus facilitating the development of innovative therapeutic modalities tailored to disrupt these interactions and ultimately improve patient outcomes in VSCC. The dysregulated ECM serves as a potent driver of SCC tumor progression, orchestrating key processes such as angiogenesis, inflammation and stromal cell behavior.
View Article and Find Full Text PDFA critical review of the progress in prevention and treatment of radiation-induced skin damage.
Front Oncol
November 2024
The Department of Obstetrics and Gynecology, West China Second University Hospital of Sichuan University, Chengdu, Sichuan, China.
Radiation therapy was initially used in dermatology to treat various skin diseases, including acne vulgaris, keloids, plantar warts, tinea capitis and hirsutism. Although it is no longer used in the treatment of many of these diseases, radiation therapy still plays a crucial role in the treatment of keloids, skin cancer and solid organ malignancies. In the past 20 years, the widespread use of intensity-modulated radiation therapy has significantly increased in the management of tumor growth in multiple cancer sites and reduced the incidence of complications in normal organs.
View Article and Find Full Text PDFHuman Papillomavirus-Related Cancer Vaccine Strategies.
Vaccines (Basel)
November 2024
Department of Gynaecology, Minhang Hospital, Fudan University, Shanghai 201199, China.
Article Synopsis
- Human papillomavirus (HPV) persistent infection is a major cause of various cancers, including cervical and head and neck cancers, but the introduction of HPV vaccines has led to a decline in these infections and associated cancers.
- A comprehensive literature review of research on HPV vaccines from 2014 to 2024 was conducted using multiple databases, confirming that these vaccines are effective and safe in preventing HPV transmission and related cancers.
- Despite their effectiveness, the global vaccination rate remains low, especially in low-income regions, presenting challenges that could be addressed by improving accessibility and developing new vaccine options.
A New Prescription Emollient Device (PED) For Psoriasis of Sensitive Areas and Folds: A Randomized Prospective Open Trial.
Psoriasis (Auckl)
November 2024
Dermatology Clinic, University of Catania, Catania, Italy.
Article Synopsis
- The study evaluated a new prescription emollient device (PED) cream for treating mild-to-moderate psoriasis in sensitive areas, focusing on its effectiveness and tolerability.
- Thirty patients applied the cream twice daily for 8 weeks, with assessments measuring symptoms like erythema and itching at baseline, 4 weeks, and 8 weeks.
- Results showed significant improvements in skin symptoms by 8 weeks, with no serious side effects, indicating that the PED could be a beneficial option for treating psoriasis in challenging areas.
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